CAJ | 학술논문

利用乳液聚合方法，以甲基丙烯酸、丙烯酸乙酯为主要原料，成功制得了一种肠溶型药用包衣材料。讨论了乳化剂的种类、配比、用量以及加料方式对乳液性能的影响。研究结果表明：以阴／非离子乳化剂配比为3：1的乳化体系制得的乳液性能较好，其中乳化剂总量为3％时，乳液粒径小，涂膜附着力为1级。
이용유액취합방법，이갑기병희산、병희산을지위주요원료，성공제득료일충장용형약용포의재료。토론료유화제적충류、배비、용량이급가료방식대유액성능적영향。연구결과표명：이음／비리자유화제배비위3：1적유화체계제득적유액성능교호，기중유화제총량위3％시，유액립경소，도막부착력위1급。
A kind of enteric coated pharmaceutical coating material was prepared by emulsion polymeriza- tion, with methyl methacrylate, ethyl acrylate as the main raw material. The effects of emulsifiers type, which under the ratio ,the amount used and the feeding mode on the properties of emulsion were investigated. The results showed that when anionie/nonionicratio emulsifier was 3 : 1 the emulsion showed good properties, when the total emulsifier was 3%, the size of emulsion is smaller, and the film showed good stability, adhesion 1 level.