CAJ | 학술논문

目的：分析普芦卡必利作为一种新型5-HT4激动剂对慢性便秘的治疗作用。方法：收集普芦卡必利治疗慢性便秘的文献，分析其疗效和安全性。结果与结论：普芦卡必利对慢性便秘，尤其对缓泻剂治疗失败的女性便秘患者是一个良好的治疗药物，对于其他动力紊乱性疾病也可能有效。截至目前的研究提示普芦卡必利的安全性良好。
목적：분석보호잡필리작위일충신형5-HT4격동제대만성편비적치료작용。방법：수집보호잡필리치료만성편비적문헌，분석기료효화안전성。결과여결론：보호잡필리대만성편비，우기대완사제치료실패적녀성편비환자시일개량호적치료약물，대우기타동력문란성질병야가능유효。절지목전적연구제시보호잡필리적안전성량호。
Objective: To analyze the efifcacy of Prucalopride, a novel 5-HT4 receptor agonist,in the treatment of chronic constipation.Methods: Current literatures regarding on the efficacy and the safety of prucalopridefor the treatment of chronic constipation were col ected and analyzed. Results and Conclusion: Prucalopride is an important medicine treating chronic constipation, especial y in females poorly responding to laxatives. There is also the possibility that it might be of beneift to other disorders of gastrointestinal motility. The safety proifle of the drug to date is favorable.