广东化工
廣東化工
엄동화공
GUANGDONG CHEMICAL INDUSTRY
2012年
18期
3-5
,共3页
王彩霞%黄跃龙%陈佳阳%乐学义
王綵霞%黃躍龍%陳佳暘%樂學義
왕채하%황약룡%진가양%악학의
琥珀酸酰壳聚糖%铜(II)配合物%苯并眯唑衍生物%抗菌活性
琥珀痠酰殼聚糖%銅(II)配閤物%苯併瞇唑衍生物%抗菌活性
호박산선각취당%동(II)배합물%분병미서연생물%항균활성
succinyl-chitosan%copper(II)complexes%benzimidazolederivatives%antibacterialactivities
文章利用琥珀酸酐对壳聚糖进行改性,并合成了两个新的蓐己合物:sucts—Cu(II)-hpb(1)和sucts-Cu(II)-tbz(2)[sucts=琥珀酰化壳聚糖,hpb--2-(2’-吡啶)-苯并咪唑,tbz=2-(4’-噻唑基)苯并咪唑]。应用红外光谱,紫外一可见光谱,原子吸收光谱对配合物进行了表征,采用试管倍比稀释法研究了这些配合物对苏云金杆菌、枯草芽孢杆菌、大肠杆菌和金黄色葡萄球菌的抑制作用。结果表明,两种配合物对四种细菌均有较强的抑菌活性,配合物I、2,最小抑菌浓度(MIC)分别为62.5~125μg·mL^-1和125~250μg·mL^-1,抗菌效果明显强于自由配体。
文章利用琥珀痠酐對殼聚糖進行改性,併閤成瞭兩箇新的蓐己閤物:sucts—Cu(II)-hpb(1)和sucts-Cu(II)-tbz(2)[sucts=琥珀酰化殼聚糖,hpb--2-(2’-吡啶)-苯併咪唑,tbz=2-(4’-噻唑基)苯併咪唑]。應用紅外光譜,紫外一可見光譜,原子吸收光譜對配閤物進行瞭錶徵,採用試管倍比稀釋法研究瞭這些配閤物對囌雲金桿菌、枯草芽孢桿菌、大腸桿菌和金黃色葡萄毬菌的抑製作用。結果錶明,兩種配閤物對四種細菌均有較彊的抑菌活性,配閤物I、2,最小抑菌濃度(MIC)分彆為62.5~125μg·mL^-1和125~250μg·mL^-1,抗菌效果明顯彊于自由配體。
문장이용호박산항대각취당진행개성,병합성료량개신적욕기합물:sucts—Cu(II)-hpb(1)화sucts-Cu(II)-tbz(2)[sucts=호박선화각취당,hpb--2-(2’-필정)-분병미서,tbz=2-(4’-새서기)분병미서]。응용홍외광보,자외일가견광보,원자흡수광보대배합물진행료표정,채용시관배비희석법연구료저사배합물대소운금간균、고초아포간균、대장간균화금황색포도구균적억제작용。결과표명,량충배합물대사충세균균유교강적억균활성,배합물I、2,최소억균농도(MIC)분별위62.5~125μg·mL^-1화125~250μg·mL^-1,항균효과명현강우자유배체。
Chitosan was modified by the way of succinic anhydride and two new copper( II ) complexes: sucts-Cu( II )- hpb(1) and sucts-Cu( II )-tbz(2), where sucts, hpb and tbz are the succinyl-chitosan, 2-(2'-pyridyl) benzimidazole and 2-(4'-thiazolyl)benzimidazole, respectively, were synthesized and characterized by infrared absorption spectrum, electronic absorption spectrum and atomic absorption spectrometry. The complexes were tested for their ability to inhibit the growth of B. Thuringiensis(G-), B. Subtilis(G+), E. Co i (G-) and S. Aureus (G+). The results showed that the minimum inhibitory concentrations of complexes 1 and 2 were 62.5-125 μg.mL-1 and 125-250 μg.mL-1, respectively.