常州工学院学报
常州工學院學報
상주공학원학보
JOURNAL OF CHANGZHOU INSTITUTE OF TECHNOLOGY
2012年
4期
45-48
,共4页
吲哚拉辛%流动注射%化学发光%KMnO4%Na2SO3
吲哚拉辛%流動註射%化學髮光%KMnO4%Na2SO3
신타랍신%류동주사%화학발광%KMnO4%Na2SO3
cinmetacin%flow injection%chemiluminescence%KMnO4%Na2 SO3
吲哚拉辛是一种非甾体抗炎镇痛药。基于吲哚拉辛对Na2SO3和酸性KMnO4的弱化学发光体系的增敏作用,建立了一种快速、灵敏、低成本的流动注射化学发光分析方法检测吲哚拉辛,探讨了发光反应机理。在优化的实验条件下,化学发光强度与吲哚拉辛的浓度在3.0×10-7～4.5×10-6mol/L内呈线性关系,相关系数为0.998 4,检测限为8.0×10-8mol/L（3σ）,平均测定5.0×10-7mol/L吲哚拉辛11次的相对偏差为2.3%。
吲哚拉辛是一種非甾體抗炎鎮痛藥。基于吲哚拉辛對Na2SO3和痠性KMnO4的弱化學髮光體繫的增敏作用,建立瞭一種快速、靈敏、低成本的流動註射化學髮光分析方法檢測吲哚拉辛,探討瞭髮光反應機理。在優化的實驗條件下,化學髮光彊度與吲哚拉辛的濃度在3.0×10-7～4.5×10-6mol/L內呈線性關繫,相關繫數為0.998 4,檢測限為8.0×10-8mol/L（3σ）,平均測定5.0×10-7mol/L吲哚拉辛11次的相對偏差為2.3%。
신타랍신시일충비치체항염진통약。기우신타랍신대Na2SO3화산성KMnO4적약화학발광체계적증민작용,건립료일충쾌속、령민、저성본적류동주사화학발광분석방법검측신타랍신,탐토료발광반응궤리。재우화적실험조건하,화학발광강도여신타랍신적농도재3.0×10-7～4.5×10-6mol/L내정선성관계,상관계수위0.998 4,검측한위8.0×10-8mol/L（3σ）,평균측정5.0×10-7mol/L신타랍신11차적상대편차위2.3%。
Cinmetacin is a nonsteroidal anti-inflammatory agent. A rapid chemiluminescence method is described for the determination of cinmetacin by combining the flow injection technique and its sensitizing effect on the weak chemiluminescence reaction between sulfite and acidic permanganate. A mechanism for the chemiluminescence reaction has been proposed. The optimum conditions for the chemiluminescence emission were intensity. Cinmetacin can be determined over the concentration range of 3.0×10-7~4.5×10-6mol/L with a correlation coefficient of 0. 998 4 and a detection limit of 8.0× 10^ -8 mol/L (3σ)). The relative standard deviation (RSD) for 11 repetitive determinations of 5.0 ×10-7 mol/L cinmetacin is 2. 3 %. The method was applied to the determination of ktoprofen in synthesized samples.
