CAJ | 학술논문

试验用商品化鸡传染性法氏囊病三价活疫苗3倍、4倍和5倍剂量分别免疫10日龄法氏囊非免疫雏鸡，免疫后3d、7d、21d剖杀，观察法氏囊的变化；免疫后7d接种ND疫苗，接种ND疫苗后14d和21d分别采血进行NDHI抗体的测定。结果显示，IBD三价活疫苗5倍免疫剂量可引起法氏囊不可逆损伤，并对ND的HI抗体产生干扰作用。
시험용상품화계전염성법씨낭병삼개활역묘3배、4배화5배제량분별면역10일령법씨낭비면역추계，면역후3d、7d、21d부살，관찰법씨낭적변화；면역후7d접충ND역묘，접충ND역묘후14d화21d분별채혈진행NDHI항체적측정。결과현시，IBD삼개활역묘5배면역제량가인기법씨낭불가역손상，병대ND적HI항체산생간우작용。
Ten days chicken were divided into 3 groups, 15 in each one.those were oral immunizined with 3, 4 and 5 times immunizing dose of trivalent vaccine to infectious bursa disease, respectively. 3 - 7 and 21 clays after immunization, 4 from each group were dissected to observe the changes of bursa.Others in groups were inoculated with vaccine of Newcastle' s disease at the time of 7 days after immunication of oral trivalent vaccine of infectious bursa disease, blood samples were collected and detected the antibodies against New Castle' s disease using the method of HI (hemagglutin inhibition test) when 14 days and 21 clays of immunication of vaccine to New Castle' s disease.The result is that the damages of bursa were visible and the produce of antibodies against New Castle' s disease was interfered when immunized by 5 times of immunizing dose.