国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2014年
15期
2330-2332
,共3页
酮酸片%卡托普利%糖尿病肾病%蛋白尿
酮痠片%卡託普利%糖尿病腎病%蛋白尿
동산편%잡탁보리%당뇨병신병%단백뇨
Acid tablets%Captopril%Diabetic nephropathy%Proteinuria
目的 了解酮酸片联合卡托普利治疗糖尿病肾病临床蛋白尿的临床效果.方法 对2011年12月至2013年12月收治的确诊为糖尿病肾病临床蛋白尿患者进行抽样,选取100例患者随机分成两组进行对比观察,其中对照组予以胰岛素强化血糖控制,口服卡托普利,实验组在强化血糖控制的基础上加以复方α-酮酸片进行治疗,比较两组患者尿蛋白排泄量、血浆清蛋白量与临床治疗效果.结果 总有效率实验组(98％)显著优于对照组(82％),两组比较差异具有统计学意义(P＜0.05).实验组16例24h尿蛋白定量＜0.5 g/L,3例为0.5～1.0 g/L;对照组15例24 h尿蛋白定量＜0.5 g/L,4例为0.5 ～ 1.0 g/L;实验组1例血浆清蛋白量＜25g/L,对照组2例,两组比较差异有统计学意义(P＜0.05).结论 针对糖尿病肾病临床蛋白尿患者而言,基于低蛋白饮食与血脂、血糖、血压控制等治疗基础上,采用复方α-酮酸片联合卡托普利进行治疗,有助于减少蛋白尿,控制糖尿病肾病进展.
目的 瞭解酮痠片聯閤卡託普利治療糖尿病腎病臨床蛋白尿的臨床效果.方法 對2011年12月至2013年12月收治的確診為糖尿病腎病臨床蛋白尿患者進行抽樣,選取100例患者隨機分成兩組進行對比觀察,其中對照組予以胰島素彊化血糖控製,口服卡託普利,實驗組在彊化血糖控製的基礎上加以複方α-酮痠片進行治療,比較兩組患者尿蛋白排洩量、血漿清蛋白量與臨床治療效果.結果 總有效率實驗組(98％)顯著優于對照組(82％),兩組比較差異具有統計學意義(P＜0.05).實驗組16例24h尿蛋白定量＜0.5 g/L,3例為0.5～1.0 g/L;對照組15例24 h尿蛋白定量＜0.5 g/L,4例為0.5 ～ 1.0 g/L;實驗組1例血漿清蛋白量＜25g/L,對照組2例,兩組比較差異有統計學意義(P＜0.05).結論 針對糖尿病腎病臨床蛋白尿患者而言,基于低蛋白飲食與血脂、血糖、血壓控製等治療基礎上,採用複方α-酮痠片聯閤卡託普利進行治療,有助于減少蛋白尿,控製糖尿病腎病進展.
목적 료해동산편연합잡탁보리치료당뇨병신병림상단백뇨적림상효과.방법 대2011년12월지2013년12월수치적학진위당뇨병신병림상단백뇨환자진행추양,선취100례환자수궤분성량조진행대비관찰,기중대조조여이이도소강화혈당공제,구복잡탁보리,실험조재강화혈당공제적기출상가이복방α-동산편진행치료,비교량조환자뇨단백배설량、혈장청단백량여림상치료효과.결과 총유효솔실험조(98％)현저우우대조조(82％),량조비교차이구유통계학의의(P＜0.05).실험조16례24h뇨단백정량＜0.5 g/L,3례위0.5～1.0 g/L;대조조15례24 h뇨단백정량＜0.5 g/L,4례위0.5 ～ 1.0 g/L;실험조1례혈장청단백량＜25g/L,대조조2례,량조비교차이유통계학의의(P＜0.05).결론 침대당뇨병신병림상단백뇨환자이언,기우저단백음식여혈지、혈당、혈압공제등치료기출상,채용복방α-동산편연합잡탁보리진행치료,유조우감소단백뇨,공제당뇨병신병진전.
Objective To investigate the clinical effect of keto acid tablets combined with captopril therapy proteinuria in diabetic nephropathy patients.Methods In our hospital from 2011 December to 2013 December among patients diagnosed as diabetic nephropathy and clinical proteinuria were sampled,we selected 100 cases of patients and randomly divided them into two groups,and then observed and compared,control group was given insulin intensive glucose control,oral captopril,the experimental group on the basis of strengthening blood sugar control,was given keto analogues tablets for treatment,plasma albumin level and clinical therapeutic efficacy were compared in two groups with proteinuria excretion.Results The total effective rate of the experimental group (98％) was significantly better than that of the control group (82％),the difference was statistically significant (P＜ 0.05).The experimental group with 16 cases of 24 h proteinuria ＜ 0.5g/L,3 cases of 0.5-1.0 g/L; the control group had 15 cases 24 h proteinuria ＜ 0.5 g/L,4 cases of 0.5-1.0 g/L; 1 case in experimental group plasma albumin content ＜ 25 g/L,2 cases in the control group,there was statistical significant difference between two groups (P ＜ 0.05).Conclusion The clinical proteinuria in diabetic nephropathy patients,based on the low protein diet and blood lipids,blood glucose,blood pressure control and treatment,with keto analogues tablets combined treatment for captopril,can help to reduce proteinuria,and control the progress of diabetic nephropathy.
