CAJ | 학술논문

采用Perkin反应合成肉桂酸,以苯甲醛和乙酸酐为原料,研究了碱性催化剂无水醋酸钾与无水碳酸钾的催化活性,证实无水碳酸钾的催化活性优于无水醋酸钾。进一步以无水碳酸钾为催化剂,设计正交实验,得到合成肉桂酸的最佳工艺参数。研究结果表明：合成肉桂酸的最佳合成条件为苯甲醛与乙酸酐的摩尔比为1∶3,反应时间为90min,苯甲醛与无水碳酸钾的摩尔比为1∶1,在此条件下所合成的肉桂酸样品,产率61.2%,产品纯度达到97%以上。
채용Perkin반응합성육계산,이분갑철화을산항위원료,연구료감성최화제무수작산갑여무수탄산갑적최화활성,증실무수탄산갑적최화활성우우무수작산갑。진일보이무수탄산갑위최화제,설계정교실험,득도합성육계산적최가공예삼수。연구결과표명：합성육계산적최가합성조건위분갑철여을산항적마이비위1∶3,반응시간위90min,분갑철여무수탄산갑적마이비위1∶1,재차조건하소합성적육계산양품,산솔61.2%,산품순도체도97%이상。
In this paper,cinnamic acid is synthesized by using the Perkin reaction.The catalytic activity of the conventional catalysts such as anhydrous potassium acetate and anhydrous potassium carbonate is analyzed,and the results show that the catalytic activity of anhydrous potassium carbonate is superior to anhydrous potassium acetate.With the orthogonal experiments and anhydrous potassium carbonate as the catalyst,the cinnamic acid is synthesized in the optimum process parameters as follows: benzaldehyde∶ acetic anhydride=1∶3,reaction time 90 min,benzaldehyde∶ potassium carbonate=1∶1 conditions,with 61.2% of the yield and above 97% of the purity.