实用临床医药杂志
實用臨床醫藥雜誌
실용림상의약잡지
JOURNAL OF JIANGSU CLINICAL MEDICINE
2014年
7期
97-99
,共3页
瑞芬太尼%芬太尼%肥胖%麻醉
瑞芬太尼%芬太尼%肥胖%痳醉
서분태니%분태니%비반%마취
remifentanil%fentanyl%obese patients%anesthesia
目的：观察瑞芬太尼、芬太尼在肥胖患者麻醉中的有效性和安全性。方法选择本院2012年10月-2013年10月拟全身麻醉手术的肥胖患者96例，采用隐藏数字随机法分为3组，每组32例，分别采用瑞芬太尼、芬太尼、瑞芬太尼复合芬太尼麻醉，比较3组血流动力学，采用视觉模拟评分（VAS）和镇静/警觉评分（OAA /S）。结果诱导前、插管前3组患者MAP 比较差异无统计学意义（P ＞0．05）。插管后芬太尼 MAP 明显升高，与瑞芬太尼组、联合组比较差异有统计学意义（P ＜0．05），拔管时瑞芬太尼组 MAP 明显升高，与芬太尼组、联合组比较差异有统计学意义（P ＜0．05）。瑞芬太尼组 VAS 评分明显高于芬太尼组、联合组，芬太尼组 OAA /S 评分明显低于瑞芬太尼组、联合组，组间比较差异有统计学意义（P ＜0．05）。结论肥胖患者麻醉中瑞芬太尼复合芬太尼在有效性与安全性方面具有较大优势。
目的：觀察瑞芬太尼、芬太尼在肥胖患者痳醉中的有效性和安全性。方法選擇本院2012年10月-2013年10月擬全身痳醉手術的肥胖患者96例，採用隱藏數字隨機法分為3組，每組32例，分彆採用瑞芬太尼、芬太尼、瑞芬太尼複閤芬太尼痳醉，比較3組血流動力學，採用視覺模擬評分（VAS）和鎮靜/警覺評分（OAA /S）。結果誘導前、插管前3組患者MAP 比較差異無統計學意義（P ＞0．05）。插管後芬太尼 MAP 明顯升高，與瑞芬太尼組、聯閤組比較差異有統計學意義（P ＜0．05），拔管時瑞芬太尼組 MAP 明顯升高，與芬太尼組、聯閤組比較差異有統計學意義（P ＜0．05）。瑞芬太尼組 VAS 評分明顯高于芬太尼組、聯閤組，芬太尼組 OAA /S 評分明顯低于瑞芬太尼組、聯閤組，組間比較差異有統計學意義（P ＜0．05）。結論肥胖患者痳醉中瑞芬太尼複閤芬太尼在有效性與安全性方麵具有較大優勢。
목적：관찰서분태니、분태니재비반환자마취중적유효성화안전성。방법선택본원2012년10월-2013년10월의전신마취수술적비반환자96례，채용은장수자수궤법분위3조，매조32례，분별채용서분태니、분태니、서분태니복합분태니마취，비교3조혈류동역학，채용시각모의평분（VAS）화진정/경각평분（OAA /S）。결과유도전、삽관전3조환자MAP 비교차이무통계학의의（P ＞0．05）。삽관후분태니 MAP 명현승고，여서분태니조、연합조비교차이유통계학의의（P ＜0．05），발관시서분태니조 MAP 명현승고，여분태니조、연합조비교차이유통계학의의（P ＜0．05）。서분태니조 VAS 평분명현고우분태니조、연합조，분태니조 OAA /S 평분명현저우서분태니조、연합조，조간비교차이유통계학의의（P ＜0．05）。결론비반환자마취중서분태니복합분태니재유효성여안전성방면구유교대우세。
Objective To explore the efficacy and safety of remifentanil and fentanyl in obese patients.Methods 96 obese patients applied general anesthesia in our hospital from October 2012 to October 2013 were randomly equally divided into three groups by hidden numbers.They were used remifentanil,fentanyl,remifentanil fentanyl fentanyl anesthesia.The hemodynamics was compared in the three groups,using the visual analogue scale (VAS)and sedation /alertness score (OAA /S).Results Before induction,the difference was not significant in intubation MAP of three groups (P >0.05).MAP significantly increased after intubation in fentanyl group, compared with the combined group and remifentanil group .The difference was significant . (P <0.05).Compared with the fentanyl group,MAP in extubation remifentanil group signifi-cantly increased.joint group difference was significant (P <0.05).VAS score in Remifentanil group was significantly higher than that in the fentanyl group,OAA /S score in combined group and the fentanyl group was significantly lower than that in remifentanil group.The difference was significant with the comparison of different groups.(P <0.05).Conclusion The efficacy and safety of remifentanil and fentanyl anesthesia in obese patients have greater advantages.
