CAJ | 학술논문

目的探讨奥曲肽联合洛赛克治疗肝硬化上消化道出血临床疗效.方法将76例临床诊断的患者随机分成奥曲肽联合洛赛克组(A组,n=39例)和垂体后叶素组(B组,n=37例),A组给予奥曲肽0.1Mg静脉推注,然后以30μg/h持续静脉滴注48~72h,洛赛克40Mg静脉推注；B组给予垂体后叶素6U静脉推注,然后以3U/h微泵维持48~72h,洛赛克40Mg静脉推注.结果 A组总有效率均明显高于B组(P<0.05).结论奥曲肽联合洛赛克治疗肝硬化上消化道出血比垂体后叶素联合洛赛克具有更好疗效,值得临床推广.
목적탐토오곡태연합락새극치료간경화상소화도출혈림상료효.방법장76례림상진단적환자수궤분성오곡태연합락새극조(A조,n=39례)화수체후협소조(B조,n=37례),A조급여오곡태0.1Mg정맥추주,연후이30μg/h지속정맥적주48~72h,락새극40Mg정맥추주；B조급여수체후협소6U정맥추주,연후이3U/h미빙유지48~72h,락새극40Mg정맥추주.결과 A조총유효솔균명현고우B조(P<0.05).결론오곡태연합락새극치료간경화상소화도출혈비수체후협소연합락새극구유경호료효,치득림상추엄.
Objective:To investigate the clinical effects of octreotide coMbining with OMeprazole on upper aliMentary tractheMorrhage coMplicated froMliver cirrhosis.Methods:Seventy six patients with clinically confirMed were randoMly divided into octreotide coMbining with OMeprazolegroup (group A,n=39),and Pituitringroup (group B,n=37).Group A wasgiven octreotide 0.1Mgintravenous injection in bolus,and then 30μg/h intravenous infusion continuously for 48~72h,OMeprazole 40Mgintravenous injection;whilegroup B wasgiven Pituitrin 6 U intravenous injection in bolus,and then 3μg/h intravenous infusion continuously for 48~72h,OMeprazole 40Mgintravenous injection.Results:The total effective rate ofgroup A were all significanthigher thangroup B (P<0.05).Conclusion:octreotide coMbining with OMeprazole shows better effects on upper aliMentary tractheMorrhage coMplicated froMliver cirrhosis coMpared with Pituitrin coMbining with OMeprazole,and is worth apply in large scale.