国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2013年
8期
1118-1120
,共3页
支气管哮喘%急性发作%小青龙汤%安全性
支氣管哮喘%急性髮作%小青龍湯%安全性
지기관효천%급성발작%소청룡탕%안전성
Bronchial asthma%Acute attack%Xiaoqinglongtang%Safety
目的 探讨支气管哮喘急性发作期患者采用小青龙汤治疗的效果及安全性.方法 研究中的105例支气管哮喘急性发作期患者均为来我院进行治疗的病例,将其随机分为对照组53例,采用西医常规治疗,研究组52例,给予西医常规治疗及小青龙汤治疗.14天后对两组患者的治疗效果及PEF、EOS及不良反应情况进行比较.结果 研究组的治疗总有效率为88.46％,明显高于对照组的75.47％ (P＜0.05),研究组与对照组的显效时间比较(5.7±0.9天VS7.1±1.3天)更短(P＜0.05),治疗后研究组患者的PEF由(60.35±2.71)％升高到(81.69±2.63)％,而EOS由(481.2±151.59)×106/L降低到(311.8±53.65) ×106/L,差异均具有统计学意义(P＜0.05).结论 支气管哮喘急性发作患者在西医治疗的基础上给予小青龙汤治疗能够显著的提高治疗效果,具有更好的改善肺功能的作用,对EOS水平的降低也具有较好的效果,且不增加患者的不良反应发生率,可以在临床上推广应用.
目的 探討支氣管哮喘急性髮作期患者採用小青龍湯治療的效果及安全性.方法 研究中的105例支氣管哮喘急性髮作期患者均為來我院進行治療的病例,將其隨機分為對照組53例,採用西醫常規治療,研究組52例,給予西醫常規治療及小青龍湯治療.14天後對兩組患者的治療效果及PEF、EOS及不良反應情況進行比較.結果 研究組的治療總有效率為88.46％,明顯高于對照組的75.47％ (P＜0.05),研究組與對照組的顯效時間比較(5.7±0.9天VS7.1±1.3天)更短(P＜0.05),治療後研究組患者的PEF由(60.35±2.71)％升高到(81.69±2.63)％,而EOS由(481.2±151.59)×106/L降低到(311.8±53.65) ×106/L,差異均具有統計學意義(P＜0.05).結論 支氣管哮喘急性髮作患者在西醫治療的基礎上給予小青龍湯治療能夠顯著的提高治療效果,具有更好的改善肺功能的作用,對EOS水平的降低也具有較好的效果,且不增加患者的不良反應髮生率,可以在臨床上推廣應用.
목적 탐토지기관효천급성발작기환자채용소청룡탕치료적효과급안전성.방법 연구중적105례지기관효천급성발작기환자균위래아원진행치료적병례,장기수궤분위대조조53례,채용서의상규치료,연구조52례,급여서의상규치료급소청룡탕치료.14천후대량조환자적치료효과급PEF、EOS급불량반응정황진행비교.결과 연구조적치료총유효솔위88.46％,명현고우대조조적75.47％ (P＜0.05),연구조여대조조적현효시간비교(5.7±0.9천VS7.1±1.3천)경단(P＜0.05),치료후연구조환자적PEF유(60.35±2.71)％승고도(81.69±2.63)％,이EOS유(481.2±151.59)×106/L강저도(311.8±53.65) ×106/L,차이균구유통계학의의(P＜0.05).결론 지기관효천급성발작환자재서의치료적기출상급여소청룡탕치료능구현저적제고치료효과,구유경호적개선폐공능적작용,대EOS수평적강저야구유교호적효과,차불증가환자적불량반응발생솔,가이재림상상추엄응용.
Objective To investigate the efficacy and safety of Xiaoqinglongtang in treatment for bronchial asthma patients with acute exacerbation.Methods 105 cases of bronchial asthma with acute exacerbation were selected from our hospital,they were randomly divided into control group (53 cases),given conventional Western treatment,research group (52 cases),given routine western treatment and Xiaoqinglongtang therapy.The effects,peak expiratory flow (PEF),and the eosinophil (EOS) concentration and adverse reaction rate of two groups after 14 days of treatment were compared.Results Treatment efficiency of research group (88.46％) was significantly higher than that in the control group (75.47％) (P＜0.05),the effectual time of research group (5.7 ± 0.9) days was significantly shorter than that of control group (7.1 ± 1.3) days (P＜0.05),after treatment,PEF of research group was significantly higher compared with that before treatmeut [60.35 ± 2.71) ％ vs (81.69 ± 2.63) ％],and the EOS was lower compared with that before treatment [(481.2 ± 151.59) × 106/L vs(311.8 ± 53.65) × 106/L],with significant difference (P＜0.05).Conclusion Bronchial asthma patients with acute exacerbation treated with Western medicine and the Xiaoqinglongtang therapy can significantly improve treatment effect,with better improvements in lung function,and also with good results on the EOS level reducing,without increasing the incidence of adverse reactions in patients,which can be applied in clinical practice.
