中华实验和临床感染病杂志（电子版）
中華實驗和臨床感染病雜誌（電子版）
중화실험화림상감염병잡지（전자판）
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL INFECTIOUS DISEASES(ELECTRONIC VERSION)
2014年
2期
249-252
,共4页
糖尿病%泌尿道感染%病原菌%药敏试验
糖尿病%泌尿道感染%病原菌%藥敏試驗
당뇨병%비뇨도감염%병원균%약민시험
Diabetes%Urinary tract infection%Pathogens%Drug sensitivity test
目的：探讨糖尿病合并泌尿道感染的病原菌分布特点及药敏情况。方法回顾性分析2011至2012年本院内分泌科住院的460例糖尿病合并泌尿道感染患者的病原菌分布和药敏特点，采用SPSS 17.0软件进行统计学分析。结果患者尿液革兰阴性杆菌（G-杆菌）阳性率为43.4%；革兰阳性球菌（G+球菌）阳性率为36.5%，真菌阳性率14.3%。药敏结果显示，检出的革兰阴性杆菌对氨苄青霉素、左氧氟沙星、环丙沙星、庆大霉素及复方新诺明敏感性较低，分别为7.6%、68.9%、45.2%、55.9%和31.3%；而对头孢类抗菌药物及哌拉西林敏感性较高，分别为94%～100%和100%；检出的革兰阳性球菌对万古霉素、利奈唑胺及哌拉西林敏感性较高（均为100%），耐药率均为0，其次氨苄青霉素、左氧氟沙星及链霉素，分别为70%～100%、50%和67%；对庆大霉素和红霉素敏感性较低，分别为20%和14%。结论大肠埃希菌（E. coli）仍是糖尿病患者合并尿路感染的最主要致病菌，但比例下降，而G+球菌呈现增加的趋势。此外，糖尿病患者真菌感染不容忽视。检出G-杆菌对头孢菌素及哌拉西林耐药性较低；检出G+球菌对万古霉素、利奈唑胺及哌拉西林耐药性较低。
目的：探討糖尿病閤併泌尿道感染的病原菌分佈特點及藥敏情況。方法迴顧性分析2011至2012年本院內分泌科住院的460例糖尿病閤併泌尿道感染患者的病原菌分佈和藥敏特點，採用SPSS 17.0軟件進行統計學分析。結果患者尿液革蘭陰性桿菌（G-桿菌）暘性率為43.4%；革蘭暘性毬菌（G+毬菌）暘性率為36.5%，真菌暘性率14.3%。藥敏結果顯示，檢齣的革蘭陰性桿菌對氨芐青黴素、左氧氟沙星、環丙沙星、慶大黴素及複方新諾明敏感性較低，分彆為7.6%、68.9%、45.2%、55.9%和31.3%；而對頭孢類抗菌藥物及哌拉西林敏感性較高，分彆為94%～100%和100%；檢齣的革蘭暘性毬菌對萬古黴素、利奈唑胺及哌拉西林敏感性較高（均為100%），耐藥率均為0，其次氨芐青黴素、左氧氟沙星及鏈黴素，分彆為70%～100%、50%和67%；對慶大黴素和紅黴素敏感性較低，分彆為20%和14%。結論大腸埃希菌（E. coli）仍是糖尿病患者閤併尿路感染的最主要緻病菌，但比例下降，而G+毬菌呈現增加的趨勢。此外，糖尿病患者真菌感染不容忽視。檢齣G-桿菌對頭孢菌素及哌拉西林耐藥性較低；檢齣G+毬菌對萬古黴素、利奈唑胺及哌拉西林耐藥性較低。
목적：탐토당뇨병합병비뇨도감염적병원균분포특점급약민정황。방법회고성분석2011지2012년본원내분비과주원적460례당뇨병합병비뇨도감염환자적병원균분포화약민특점，채용SPSS 17.0연건진행통계학분석。결과환자뇨액혁란음성간균（G-간균）양성솔위43.4%；혁란양성구균（G+구균）양성솔위36.5%，진균양성솔14.3%。약민결과현시，검출적혁란음성간균대안변청매소、좌양불사성、배병사성、경대매소급복방신낙명민감성교저，분별위7.6%、68.9%、45.2%、55.9%화31.3%；이대두포류항균약물급고랍서림민감성교고，분별위94%～100%화100%；검출적혁란양성구균대만고매소、리내서알급고랍서림민감성교고（균위100%），내약솔균위0，기차안변청매소、좌양불사성급련매소，분별위70%～100%、50%화67%；대경대매소화홍매소민감성교저，분별위20%화14%。결론대장애희균（E. coli）잉시당뇨병환자합병뇨로감염적최주요치병균，단비례하강，이G+구균정현증가적추세。차외，당뇨병환자진균감염불용홀시。검출G-간균대두포균소급고랍서림내약성교저；검출G+구균대만고매소、리내서알급고랍서림내약성교저。
Objective To investigate the distribution and drug sensitivity of pathogens in diabetes complicated urinary tract infection. Methods Totaol of 460 cases of diabetic patients with urinary tract infection from 2011 to 2012 underwent urine culture and sensitivity tests, statistical analysis was done by SPSS 17.0 statistical software. Results Urine of patients with Gram-negative bacilli (G-bacilli) positive rate was 43.4%;Gram-positive (G+cocci bacteria) positive rate was 36.5%and fungal positive rate of 14.3%. Susceptibility results show that the detection of Gram- bacilli to ampicillin, levofloxacin, ciprofloxacin, gentamicin and cotrimoxazole were low sensitivity (7.6%, 68.9%, 45.2%, 55.9% and 31.3%), while to cephalosporins and piperacillin with high sensitivity (94%-100%and 100%);detection of Gram+cocci to vancomycin, linezolid and piperacillin with high sensitivity (100%), resistance was 0%, followed ampicillin, levofloxacin, and streptomycin (70%-100%, 50% and 67%, respectively), gentamicin, red ADM low sensitivity (20%and 14%, respectively). Conclusions Escherichia coli (E. coli) is still the main pathogenic bacteria in diabetic patients with urinary tract infection, but the proportion was decreased, but tended to increase G+cocci. In addition, patients with diabetes fungal infections could not be ignored. Detectable G-bacilli resistant to cephalosporins and piperacillin is lower than others. Detectable G+cocci resistant to vancomycin, linezolid and piperacillin is lower than others.
