CAJ | 학술논문

低促性腺激素性腺功能减退症( hypogonadotropic hypogonadism,HH)是一种罕见的、以低促性腺激素为特征的、引起第二性征及生殖系统发育障碍的疾病。本文将对该疾病定义、病因、临床表现、诊断及治疗进行全面的介绍。由于HH主要影响育龄女性的生育力,因此诱发排卵以及恢复生育力是该疾病治疗中的关键。治疗HH促排卵的方法较正常人特殊而且复杂,本文将着重介绍HH促排卵的各种原理和方法,同时结合最新的国内外进展以及临床实践经验对各种方法的有效性进行探讨。
저촉성선격소성선공능감퇴증( hypogonadotropic hypogonadism,HH)시일충한견적、이저촉성선격소위특정적、인기제이성정급생식계통발육장애적질병。본문장대해질병정의、병인、림상표현、진단급치료진행전면적개소。유우HH주요영향육령녀성적생육력,인차유발배란이급회복생육력시해질병치료중적관건。치료HH촉배란적방법교정상인특수이차복잡,본문장착중개소HH촉배란적각충원리화방법,동시결합최신적국내외진전이급림상실천경험대각충방법적유효성진행탐토。
Hypogonadotropic hypogonadism ( HH ) is a rare disease characterized by insufficient gonadotropin release,leading to a failure of developing secondary sexual characteristics and a mature reproductive system. This paper presents the definition,etiology,clinical manifestation,diagnosis and treatment of HH thoroughly. As most HH patients are infertile due to anovulation, ovulation induction is the key step to get pregnancy. However, ovulation induction in HH patients is more complicated compared with normal patients. We will focus on introducing different ovarian stimulation protocols based on both published papers and clinical experiences.