CAJ | 학술논문

目的：通过检测慢性咳嗽和哮喘患者血清特异性IgE抗体，探讨特异性过敏原在慢性咳嗽和哮喘诊治中的作用。方法：采用蛋白印迹法检测54例慢性咳嗽和55例哮喘患者血清中特异性IgE抗体。结果：慢性咳嗽患者和哮喘患者吸入性过敏原阳性率、吸入性和食物性过敏原种类、食物性过敏原等级比较，差异均无统计学意义(P＞0.05)；两组患者总过敏原阳性率、食物性过敏原阳性率、吸入性过敏原等级比较，差异具均有统计学意义(P＜0.05)。结论：慢性咳嗽和哮喘患者过敏原检出情况不同，检测特异性过敏原对慢性咳嗽和哮喘的诊治具有指导作用。
목적：통과검측만성해수화효천환자혈청특이성IgE항체，탐토특이성과민원재만성해수화효천진치중적작용。방법：채용단백인적법검측54례만성해수화55례효천환자혈청중특이성IgE항체。결과：만성해수환자화효천환자흡입성과민원양성솔、흡입성화식물성과민원충류、식물성과민원등급비교，차이균무통계학의의(P＞0.05)；량조환자총과민원양성솔、식물성과민원양성솔、흡입성과민원등급비교，차이구균유통계학의의(P＜0.05)。결론：만성해수화효천환자과민원검출정황불동，검측특이성과민원대만성해수화효천적진치구유지도작용。
Objective:To investigate the role of speciifc allergens in diagnosis and treatment of chronic cough and asthma by detecting serum speciifc IgE antibody of chronic cough and asthma patients.Methods:The serum speciifc IgE antibody of 54 chronic cough patients and 55 asthma patients was detected by Western Blot.Results:There had no statistically signiifcant difference between patients with chronic cough and asthma about inhaled allergen positive rate, inhaled allergens species, food allergens species, food allergen levels (P>0.05). There had statistically significant difference about total allergen positive rate, food allergen positive rate, inhaled allergen levels between patients with chronic cough and asthma (P<0.05).Conclusions: The allergens detecting results of patients with chronic cough and asthma are different; detecting speciifc allergens has guiding role for diagnosis and treatment of chronic cough and asthma.