CAJ | 학술논문

目的：探讨一种适于整形外科动物实验的快速、安全、可靠的麻醉方法。方法选取82只实验用家兔，随机分为A、B、C三组，Α组肌肉注射速眠新Ⅱ（0.35 mL/kg），Β组给予10％水合氯醛静脉注射（2.5～3 mL/kg），C组肌肉注射速眠新Ⅱ（0.2 mL/kg）和静脉注射10％水合氯醛（1～1.5 mL/kg）复合麻醉，比较3组的麻醉效果，观察3组麻醉药物起效时间、麻醉维持时间、苏醒时间及动物麻醉死亡率。结果诱导期及苏醒期时长C组介于A，B两组之间（P ＜0.05）；而麻醉期时长C组与A组相当（P ＞0.05）并均高于B组（P ＜0.05）。结论速眠新Ⅱ与水合氯醛复合麻醉诱导及恢复时间短，麻醉维持时间长，死亡率低，是整形外科家兔动物实验中一种简便快速、安全有效的麻醉方法。
목적：탐토일충괄우정형외과동물실험적쾌속、안전、가고적마취방법。방법선취82지실험용가토，수궤분위A、B、C삼조，Α조기육주사속면신Ⅱ（0.35 mL/kg），Β조급여10％수합록철정맥주사（2.5～3 mL/kg），C조기육주사속면신Ⅱ（0.2 mL/kg）화정맥주사10％수합록철（1～1.5 mL/kg）복합마취，비교3조적마취효과，관찰3조마취약물기효시간、마취유지시간、소성시간급동물마취사망솔。결과유도기급소성기시장C조개우A，B량조지간（P ＜0.05）；이마취기시장C조여A조상당（P ＞0.05）병균고우B조（P ＜0.05）。결론속면신Ⅱ여수합록철복합마취유도급회복시간단，마취유지시간장，사망솔저，시정형외과가토동물실험중일충간편쾌속、안전유효적마취방법。
Objective To observe the anesthetic effect of Sumianxin Ⅱcombined with chloral hydrate in plastic surgical operation on rabbit and explore the fast , safe and effective anesthetic methods .Methods A total of 82 Rabbits for operation were randomly divided into A , B and C groups.The A group was injected with SumianxinⅡintramuscularly (0.35 mL/kg by weight).The B group was injected with 10%chloral hydrate intravenously (2.5~3 mL/kg by weight).The C group was injected with Sumianxin Ⅱintramuscularly ( 0.2 mL/kg by weight ) combined with 10% chloral hydrate intravenously(1 ~1.5 mL/kg by weight).The anesthetic effect of induction and recovery time of anesthesia ,anesthesia maintaining time ,and anesthesia mortality rate were observed and compared .Results The anesthetic effect of induction of anesthesia,recovery time of C groups fall in between which of A and B groups ( P <0.05).However, as for anesthesia maintaining time , there was no significant difference between A and C group and both the two groups were longer than B group.Conclusion SumianxinⅡcombined with chloral hydrate possess the advantages of fast anesthesia induction and recovery effect , longer anesthesia maintaining time and low mortality .Therefore it is an easy to operate , expeditious , safe and effective anesthetization for plastic surgical operation on rabbit .