国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2014年
6期
1177-1178
,共2页
昂丹司琼%小儿斜视手术%恶心呕吐
昂丹司瓊%小兒斜視手術%噁心嘔吐
앙단사경%소인사시수술%악심구토
ondansetron%pediatric strabismus surgery%nausea and vomiting
目的：不同时间静脉注射昂丹司琼在小儿斜视术后恶心呕吐(postoperative nausea and vomiting,PONV)中的效果观察。<br> 方法：随机选择2013-06/08在我院拟行斜视手术的患儿90例,ASAI~Ⅱ级,年龄3~11岁。随机分为3组,每组30例。 A组在手术开始前静脉注射昂丹司琼0.1mg/kg；B组在手术结束后静脉注射昂丹司琼0.1 mg/kg；C组为对照组,不用昂丹司琼。在术后24 h内观察患者恶心、呕吐的发生例数及严重程度。<br> 结果：三组患者的性别、体重、年龄、麻醉时间、氯胺酮用量各组间比较无统计学意义(P>0.05)。 A,B组的PONV发生率明显低于C组(P<0.05),A组和B组的PONV发生率比较无统计学意义(P>0.05)。<br> 结论：在手术前或手术结束时应用昂丹司琼可有效、安全地预防小儿斜视手术后的PONV,提高眼科手术安全性,且费用低,是一种值得推广应用的止吐方法。
目的：不同時間靜脈註射昂丹司瓊在小兒斜視術後噁心嘔吐(postoperative nausea and vomiting,PONV)中的效果觀察。<br> 方法：隨機選擇2013-06/08在我院擬行斜視手術的患兒90例,ASAI~Ⅱ級,年齡3~11歲。隨機分為3組,每組30例。 A組在手術開始前靜脈註射昂丹司瓊0.1mg/kg；B組在手術結束後靜脈註射昂丹司瓊0.1 mg/kg；C組為對照組,不用昂丹司瓊。在術後24 h內觀察患者噁心、嘔吐的髮生例數及嚴重程度。<br> 結果：三組患者的性彆、體重、年齡、痳醉時間、氯胺酮用量各組間比較無統計學意義(P>0.05)。 A,B組的PONV髮生率明顯低于C組(P<0.05),A組和B組的PONV髮生率比較無統計學意義(P>0.05)。<br> 結論：在手術前或手術結束時應用昂丹司瓊可有效、安全地預防小兒斜視手術後的PONV,提高眼科手術安全性,且費用低,是一種值得推廣應用的止吐方法。
목적：불동시간정맥주사앙단사경재소인사시술후악심구토(postoperative nausea and vomiting,PONV)중적효과관찰。<br> 방법：수궤선택2013-06/08재아원의행사시수술적환인90례,ASAI~Ⅱ급,년령3~11세。수궤분위3조,매조30례。 A조재수술개시전정맥주사앙단사경0.1mg/kg；B조재수술결속후정맥주사앙단사경0.1 mg/kg；C조위대조조,불용앙단사경。재술후24 h내관찰환자악심、구토적발생례수급엄중정도。<br> 결과：삼조환자적성별、체중、년령、마취시간、록알동용량각조간비교무통계학의의(P>0.05)。 A,B조적PONV발생솔명현저우C조(P<0.05),A조화B조적PONV발생솔비교무통계학의의(P>0.05)。<br> 결론：재수술전혹수술결속시응용앙단사경가유효、안전지예방소인사시수술후적PONV,제고안과수술안전성,차비용저,시일충치득추엄응용적지토방법。
AIM: To observe the efficacy of ondansetron by intravenous injection at different time in preventing nausea and vomiting after pediatric strabismus surgery.METHODS: Totally 90 children aged 3 - 11y were randomly selected for pediatric strabismus surgery from June 2013 to August 2013 in our hospital. The ASA grade of all children were Ⅰ - II. Children were randomly divided into three groups with 30 cases each. Group A received intravenous drip of ondansetron 0. 1mg/kg before surgery. Group B received intravenous drip of ondansetron 0. 1mg/kg after surgery. Group C as control group was not given ondansetron. The number and severity of nausea and vomiting were observed within 24h after surgery. <br> RESULTS: There were no statistical significance in patients' gender, weight, age, duration of anesthesia, ketamine dosage and vital signs intraoperative between the three groups ( P > 0. 05 ). The incidence rate of postoperative nausea and vomiting ( PONV) of group A and B were significantly lower than group C (P<0. 05). The incidence rate of PONV of group A and group B have no significant difference (P>0. 05). <br> CONCLUSION:Using ondansetron is effective and safe in preventing PONV before and at the end of the pediatric strabismus surgery, which can also improve safety and be lower cost. It is a worthy promoting antiemetic approach for eye surgery.
