中国药师
中國藥師
중국약사
CHINA PHARMACIST
2014年
10期
1716-1718
,共3页
膝关节骨性关节炎%关节镜下关节清理术%玻璃酸钠
膝關節骨性關節炎%關節鏡下關節清理術%玻璃痠鈉
슬관절골성관절염%관절경하관절청리술%파리산납
Kneeosteoarthritis%Arthroscopicdebridement%Sodiumhyaluronate
目的：：探讨联合应用关节镜下关节清理术和关节腔内注射玻璃酸钠治疗膝关节炎的临床疗效。方法：膝关节骨性关节炎患者172例随机分为试验组和对照组。对照组患者实施关节镜下关节清理术，试验组在关节镜下关节清理术后给予关节腔内注射玻璃酸钠2.5 ml。对比两组患者治疗前及治疗后1周、3个月的Lequence评分、Lysholm评分和疼痛目测类比评分，以及两组治疗3个月的临床疗效。结果：治疗后1周、3个月，两组患者的Lequence评分、Lysholm评分和疼痛目测类比评分均显著低于本组前一时间点(P<0.01)；且试验组治疗后评分显著低于对照组同期(P<0.05或0.01)。试验组治疗3个月临床有效率显著高于对照组(P<0.05)。结论：关节镜清理联合腔内注射玻璃酸钠治疗膝关节骨关节炎临床疗效明显，能有效改善患者症状，值得临床应用推广。
目的：：探討聯閤應用關節鏡下關節清理術和關節腔內註射玻璃痠鈉治療膝關節炎的臨床療效。方法：膝關節骨性關節炎患者172例隨機分為試驗組和對照組。對照組患者實施關節鏡下關節清理術，試驗組在關節鏡下關節清理術後給予關節腔內註射玻璃痠鈉2.5 ml。對比兩組患者治療前及治療後1週、3箇月的Lequence評分、Lysholm評分和疼痛目測類比評分，以及兩組治療3箇月的臨床療效。結果：治療後1週、3箇月，兩組患者的Lequence評分、Lysholm評分和疼痛目測類比評分均顯著低于本組前一時間點(P<0.01)；且試驗組治療後評分顯著低于對照組同期(P<0.05或0.01)。試驗組治療3箇月臨床有效率顯著高于對照組(P<0.05)。結論：關節鏡清理聯閤腔內註射玻璃痠鈉治療膝關節骨關節炎臨床療效明顯，能有效改善患者癥狀，值得臨床應用推廣。
목적：：탐토연합응용관절경하관절청리술화관절강내주사파리산납치료슬관절염적림상료효。방법：슬관절골성관절염환자172례수궤분위시험조화대조조。대조조환자실시관절경하관절청리술，시험조재관절경하관절청리술후급여관절강내주사파리산납2.5 ml。대비량조환자치료전급치료후1주、3개월적Lequence평분、Lysholm평분화동통목측류비평분，이급량조치료3개월적림상료효。결과：치료후1주、3개월，량조환자적Lequence평분、Lysholm평분화동통목측류비평분균현저저우본조전일시간점(P<0.01)；차시험조치료후평분현저저우대조조동기(P<0.05혹0.01)。시험조치료3개월림상유효솔현저고우대조조(P<0.05)。결론：관절경청리연합강내주사파리산납치료슬관절골관절염림상료효명현，능유효개선환자증상，치득림상응용추엄。
Objective:To investigate the clinical effects of arthroscopic debridement combined with intra-articular injection of sodi-um hyaluronate in the treatment of knee osteoarthritis. Methods:One hundred and seventy-two cases with knee osteoarthritis were ran-domly divided into the treatment group and the control group. The control group received arthroscopic debridement, while the treatment group received intra-articular injection of 2. 5ml sodium hyaluronate after arthroscopic debridement. Lequence score, Lysholm score and visual analogue scale for pain were compared between the two groups before the treatment and after the 1-week and 3-month treatment, and the clinical effects were compared after the 3-month treatment as well. Results: Lequence score, Lysholm score and visual ana-logue pain scores after the treatment were lower than those before the treatment with significant differences (P <0.01) in the two groups. After the treatment,Lequence score, Lysholm score and visual analogue pain scores of the treatment group was lower than those of the control group with significant differences (P<0. 05 or 0. 01). After the 3-month treatment,the clinical efficacy of the treatment group was better than that of the control group (P<0. 05). Conclusion:Arthroscopic debridement combined with intra-articular injec-tion of sodium hyaluronate in the treatment of knee osteoarthritis has better efficacy than arthroscopic debridement alone. The combina-tion can effectively improve symptoms, which is worthy of clinical promotion.
