中国药师
中國藥師
중국약사
CHINA PHARMACIST
2014年
10期
1680-1681
,共2页
王薇%周妍%范彦博%严启伟%周才新
王薇%週妍%範彥博%嚴啟偉%週纔新
왕미%주연%범언박%엄계위%주재신
营心宁胶囊%挥发油%β-环糊精%包合物%正交试验法
營心寧膠囊%揮髮油%β-環糊精%包閤物%正交試驗法
영심저효낭%휘발유%β-배호정%포합물%정교시험법
Yingxinningcapsules%Volatileoil%β-Cyclodextrin%Clathrates%Orthogonaltest
目的：：优选营心宁胶囊中β-环糊精(β-CD)包合挥发油的最佳工艺。方法：采用L9(34)正交试验法,以包合物中含油量为考察指标,以挥发油∶β-CD、包合温度、包合时间及搅拌速度为考察因素优选工艺。结果：优选的包合工艺为：挥发油∶β-CD为1∶9,包合温度40℃,包合时间为30 min,搅拌速度800 r· min-1。结论：优选的工艺简便可行,稳定性好,挥发油提取量最高。
目的：：優選營心寧膠囊中β-環糊精(β-CD)包閤揮髮油的最佳工藝。方法：採用L9(34)正交試驗法,以包閤物中含油量為攷察指標,以揮髮油∶β-CD、包閤溫度、包閤時間及攪拌速度為攷察因素優選工藝。結果：優選的包閤工藝為：揮髮油∶β-CD為1∶9,包閤溫度40℃,包閤時間為30 min,攪拌速度800 r· min-1。結論：優選的工藝簡便可行,穩定性好,揮髮油提取量最高。
목적：：우선영심저효낭중β-배호정(β-CD)포합휘발유적최가공예。방법：채용L9(34)정교시험법,이포합물중함유량위고찰지표,이휘발유∶β-CD、포합온도、포합시간급교반속도위고찰인소우선공예。결과：우선적포합공예위：휘발유∶β-CD위1∶9,포합온도40℃,포합시간위30 min,교반속도800 r· min-1。결론：우선적공예간편가행,은정성호,휘발유제취량최고。
Objective:To optimize β-cyclodextrin (β-CD) inclusion process for volatile oil in Yingxinning capsules. Methods:The content of volatile oil in theβ-CD inclusion compound as the evaluation index, the ratio of volatile oil toβ-CD, inclusion tempera-ture, inclusion time and stirring speed as the influencing factors, the inclusion process was studied using L9(34)orthogonal design. Re-sults:The best preparation conditions were as follows:the ratio of volatile oil toβ-CD was 1∶ 9, the inclusion temperature was 40℃, the inclusion time was 30min and the stirring speed was 800 r·min-1 . Conclusion: The preparation technology is simple, feasible and stable with high inclusion rate of volatile oil.
