CAJ | 학술논문

目的：探讨脑出血患者皮质下缺血性病变程度与血管性认知功能障碍的关系。方法：选择脑出血患者124例，根据神经心理学评估不同分为：认知正常组，60例，无认知损害；认知损害组，64例，存在血管性认知功能损害。比较两组病灶直径、不同区域病灶数量、白质病变程度及NIHSS量表评分、改良Bathel指数评分差异。应用多元Logistic回归分析上述指标与认知功能障碍程度的关系。结果：与认知正常组相比，认知损害组额区与基底核区的病灶数目、病灶直径、白质病变程度及NIHSS评分较高（P＜0．05），认知损害组改良Bathel指数评分较低（P＜0．05），而颞区、顶枕区和幕下区的病灶数目无差异（P＞0．05）。应用多元Logistic回归分析示白质病变程度与认知功能障碍程度有正相关性（OR＝4．705，P＝0．009）。结论：脑出血患者白质缺血性病变程度能有效评估血管性认知功能障碍程度。
목적：탐토뇌출혈환자피질하결혈성병변정도여혈관성인지공능장애적관계。방법：선택뇌출혈환자124례，근거신경심이학평고불동분위：인지정상조，60례，무인지손해；인지손해조，64례，존재혈관성인지공능손해。비교량조병조직경、불동구역병조수량、백질병변정도급NIHSS량표평분、개량Bathel지수평분차이。응용다원Logistic회귀분석상술지표여인지공능장애정도적관계。결과：여인지정상조상비，인지손해조액구여기저핵구적병조수목、병조직경、백질병변정도급NIHSS평분교고（P＜0．05），인지손해조개량Bathel지수평분교저（P＜0．05），이섭구、정침구화막하구적병조수목무차이（P＞0．05）。응용다원Logistic회귀분석시백질병변정도여인지공능장애정도유정상관성（OR＝4．705，P＝0．009）。결론：뇌출혈환자백질결혈성병변정도능유효평고혈관성인지공능장애정도。
Objective To investigate the correlation between the severity of subcortical ischemic lesions and vascular cognitive impairment in encephalorrhagia patients. Methods One hundred and twenty-four encephalorrhagia patients were enrolled into two groups, the normal cognition group (60 cases, without cognitive impairment) and the cognitive impairment group (64 cases, with vascular cognitive impairment). Parameters of the lesion diameters, various lesion locations, white matter lesions severity and NIHSS scale score, modified Bathel index score were compared between these two groups. The correlations between the above indexes and the vascular cognitive impairment degree were analyzed by Logistic regression proceduress. Results Compared to the normal cognition group, the indexes of lesion number of frontal area and basal ganglia, lesion diameters, white-matter severity and NIHSS scale score of cognitive impairment group were higher (P<0.05, respectively), and the modified Bathel index score was lower (P<0.05), but the lesion number in temporal, parieto-occipital and infratentorial area were not changed (P>0.05, respectively) in the cognitive impairment group. Result of Logistic regression analysis showed a positive correlation between the severity of white-matter and the degree of vascular cognitive impairment (OR =4.705, P=0.009). Conclusion The severity of white-matter can effectively assess the degree of vascular cognitive impairment of encephalorrhagia patients.