中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2014年
11期
28-30
,共3页
八珍汤加味%糖尿病周围神经病变%神经传导速度%药渣熏洗
八珍湯加味%糖尿病週圍神經病變%神經傳導速度%藥渣熏洗
팔진탕가미%당뇨병주위신경병변%신경전도속도%약사훈세
Bazhen decoction%Dregs of diabetic peripheral neuropathy%Nerve conduction velocity%Fumigation
目的:观察八珍汤加味治疗糖尿病周围神经病变的临床疗效。方法:将60例糖尿病周围神经病变患者随机分为治疗组和对照组各30例,在降血糖治疗基础上,对照组静滴牛痘疫苗致炎兔皮提取物注射液6mL、口服拜阿司匹林片,每晚一次,1片/次,甲钴胺3次/d,0.5mg/次。治疗组在上述基础上加服八珍汤加味,1剂/d,并留药渣熏洗下肢,2次/d,30min/次,两组治疗10d为1个疗程,2个疗程后观察疗效,并比较两组治疗前后主要中医症状积分(受累下肢感觉、神经分布区发生疼痛、麻木、发凉、踩棉花感)及总积分,神经传导速度(腓总神经、胫神经、正中神经、腓肠神经)的变化。结果:治疗组总有效率80.00%,对照组总有效率60.00%,治疗组临床效果明显优于对照组(P<0.01),两组治疗后主要中医症状积分及总积分均有改善,治疗组主要中医症状积分及总积分改善明显优于对照组(P<0.05或 P<0.01),治疗后治疗组各条神经传导速度改善明显优于对照组(P<0.05)。结论:八珍汤加味治疗糖尿病周围神经病变,临床疗效肯定。
目的:觀察八珍湯加味治療糖尿病週圍神經病變的臨床療效。方法:將60例糖尿病週圍神經病變患者隨機分為治療組和對照組各30例,在降血糖治療基礎上,對照組靜滴牛痘疫苗緻炎兔皮提取物註射液6mL、口服拜阿司匹林片,每晚一次,1片/次,甲鈷胺3次/d,0.5mg/次。治療組在上述基礎上加服八珍湯加味,1劑/d,併留藥渣熏洗下肢,2次/d,30min/次,兩組治療10d為1箇療程,2箇療程後觀察療效,併比較兩組治療前後主要中醫癥狀積分(受纍下肢感覺、神經分佈區髮生疼痛、痳木、髮涼、踩棉花感)及總積分,神經傳導速度(腓總神經、脛神經、正中神經、腓腸神經)的變化。結果:治療組總有效率80.00%,對照組總有效率60.00%,治療組臨床效果明顯優于對照組(P<0.01),兩組治療後主要中醫癥狀積分及總積分均有改善,治療組主要中醫癥狀積分及總積分改善明顯優于對照組(P<0.05或 P<0.01),治療後治療組各條神經傳導速度改善明顯優于對照組(P<0.05)。結論:八珍湯加味治療糖尿病週圍神經病變,臨床療效肯定。
목적:관찰팔진탕가미치료당뇨병주위신경병변적림상료효。방법:장60례당뇨병주위신경병변환자수궤분위치료조화대조조각30례,재강혈당치료기출상,대조조정적우두역묘치염토피제취물주사액6mL、구복배아사필림편,매만일차,1편/차,갑고알3차/d,0.5mg/차。치료조재상술기출상가복팔진탕가미,1제/d,병류약사훈세하지,2차/d,30min/차,량조치료10d위1개료정,2개료정후관찰료효,병비교량조치료전후주요중의증상적분(수루하지감각、신경분포구발생동통、마목、발량、채면화감)급총적분,신경전도속도(비총신경、경신경、정중신경、비장신경)적변화。결과:치료조총유효솔80.00%,대조조총유효솔60.00%,치료조림상효과명현우우대조조(P<0.01),량조치료후주요중의증상적분급총적분균유개선,치료조주요중의증상적분급총적분개선명현우우대조조(P<0.05혹 P<0.01),치료후치료조각조신경전도속도개선명현우우대조조(P<0.05)。결론:팔진탕가미치료당뇨병주위신경병변,림상료효긍정。
Objective: To observe clinical efficacy of Bazhen decoction for diabetic peripheral neuropathy. Methods: 60 patients were randomly divided into treatment group and control group, 30 cases in each. Based on the control group intravenous rabbit skin inflamed by vaccinia virus extract injection 6mL, oral Aspirin tablets, night, every time a mecobalamin 3 times / day, 0.5mg/times. Treatment groups based on the above plus clothing Bazhen decoction, daily one, and leave the dregs fumigation lower limbs, 2 courses a day, every 30 minutes, the two groups of treatment 10 days for a course of treatment was observed after 2 efficacy and compare before and after treatment mainly TCM symptom score (involved lower extremity sensory nerve distribution area occurs pain, numbness, cold, flu foot cotton) and total score, nerve conduction velocity (peroneal nerve, tibial nerve, median nerve, sural nerve) changes. Results:The treatment group was 80.00%in the control group was 60.00%, the clinical effect of the treatment group than the control group (P<0.01), after treatment, the main clinical symptoms score and total score were improved in the treatment group major TCM symptom score and total score improved significantly better than the control group (P<0.05 or P<0.01), each of the treatment group improved nerve conduction velocity than the control group (P<0.05). Conclusion: Bazhen decoction diabetic peripheral neuropathy, the clinical efficacy was sure.