CAJ | 학술논문

目的：检测尿沉渣涂片中的一种特殊病理管型，将其命名为不规则管型（irregular cast），对其在不同疾病中的阳性率进行分析研究，探讨其在泌尿系感染中的诊断意义。方法观察564例泌尿系疾病患者的尿沉渣涂片中不规则管型检出率，并通过荧光染色与瑞-姬染色方法对管型的类别进行判定，同时对中层移行上皮、表层移行上皮、白细胞等成分阳性率作对照比较。结果不规则管型在上泌尿系感染患者尿液中易见，特别是有1年以上感染史的患者。急性肾盂肾炎患者尿液中阳性率为63．4％，慢性肾盂肾炎患者尿液中阳性率为83．3％，肾结石患者尿液中不规则管型阳性率为8．1％，肾小球肾炎患者尿液中不规则管型阳性率为5．8％，膀胱炎、尿道炎、前列腺炎、肾囊肿患者尿液中未见。急性肾盂肾炎和慢性肾盂肾炎患者尿液中不规则管型阳性率与其他各类患者比较，差异有统计学意义（P＜0．05）。结论不规则管型是一种特殊类型的管型，在形态上比中层移行上皮细胞更易识别，对上泌尿系感染有重要诊断意义，同时对感染性肾脏损伤有重要的临床作用。
목적：검측뇨침사도편중적일충특수병리관형，장기명명위불규칙관형（irregular cast），대기재불동질병중적양성솔진행분석연구，탐토기재비뇨계감염중적진단의의。방법관찰564례비뇨계질병환자적뇨침사도편중불규칙관형검출솔，병통과형광염색여서-희염색방법대관형적유별진행판정，동시대중층이행상피、표층이행상피、백세포등성분양성솔작대조비교。결과불규칙관형재상비뇨계감염환자뇨액중역견，특별시유1년이상감염사적환자。급성신우신염환자뇨액중양성솔위63．4％，만성신우신염환자뇨액중양성솔위83．3％，신결석환자뇨액중불규칙관형양성솔위8．1％，신소구신염환자뇨액중불규칙관형양성솔위5．8％，방광염、뇨도염、전렬선염、신낭종환자뇨액중미견。급성신우신염화만성신우신염환자뇨액중불규칙관형양성솔여기타각류환자비교，차이유통계학의의（P＜0．05）。결론불규칙관형시일충특수류형적관형，재형태상비중층이행상피세포경역식별，대상비뇨계감염유중요진단의의，동시대감염성신장손상유중요적림상작용。
Objective To detect a special pathological cast named irregular cast of Urine sediments ,investigate the positive rate of irregular cast in different diseases and investigate the diagnostic significance in urinary tract infec-tion .Methods The irregular cast were examined in the urinary sediments of 564 patients with the urinary system diseases .The fluorescent staining and the Giemsa staining were used for determining the types of the cells .Mean-while ,Middle transitional epithelium ,Surface transitional epithelium and the number of leucocytes were treated as the control .Results Irregular cast is easy to be seen in the urinary sediments of patients with urinary tract infection ,es-pecially who has this disease more than one year .The positive rate was 63 .4% in the acute pyelonephritis ,83 .3% in the chronic pyelonephritis ,8 .1% in the renal calculi ,5 .8% in the Glomerulonephritis .No Irregular cast was found in the urines of cystitis ,urethritis ,prostatitis ,and renal cyst .The positive rate of Irregular cast in the acute pyelonephri-tis and the chronic pyelonephritis was significantly higher than those in the other groups (P<0 .05) .Conclusion The irregular cast is a special cast ,is easier to be identified than Middle transitional epithelium .It plays an important role in diagnosising the upper urinary tract infection and the infectious kidney damage .