CAJ | 학술논문

目的：探讨输血速度及输血量对重型颅脑损伤患者凝血功能的影响。方法对该院60例重型颅脑损伤患者输血前、后凝血功能指标进行检测并对比分析。结果重型颅脑损伤患者输血后凝血酶原时间（P T ）、活化部分凝血酶原时间（APTT）、凝血酶时间（TT）显著增加，并且输血速度较快、输血量较大的患者凝血功能指标的改变更加明显。结论重型颅脑损伤患者输血速度较快、输血量较大会加重患者的凝血障碍，应及时补充血浆，以改善其凝血功能，提高临床输血疗效。
목적：탐토수혈속도급수혈량대중형로뇌손상환자응혈공능적영향。방법대해원60례중형로뇌손상환자수혈전、후응혈공능지표진행검측병대비분석。결과중형로뇌손상환자수혈후응혈매원시간（P T ）、활화부분응혈매원시간（APTT）、응혈매시간（TT）현저증가，병차수혈속도교쾌、수혈량교대적환자응혈공능지표적개변경가명현。결론중형로뇌손상환자수혈속도교쾌、수혈량교대회가중환자적응혈장애，응급시보충혈장，이개선기응혈공능，제고림상수혈료효。
Objective To investigate the coagulation function changes with different speed and different vol-ume of blood transfusion in patients with severe traumatic brain injury .Methods Coagulation parameters of 60 pa-tients with severe traumatic brain injury were detected and analyzed before and after blood transfusion .Results pro-thrombin time ,activated partial thromboplastin time ,thrombin time was significantly changed in patients with severe traumatic brain injury after transfusion while patients with faster and more blood transfusion ,changed more pro-nounced .Conclusion Inappropriate speed and volume of blood transfusion in patients with severe traumatic brain in-jury will deteriorate coagulation dysfunction ,plasma should be promptly added to improve its coagulation function and blood transfusion efficacy .