中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2014年
15期
20-21
,共2页
解脲支原体%耐药性%药物敏感试验
解脲支原體%耐藥性%藥物敏感試驗
해뇨지원체%내약성%약물민감시험
Ureaplasma urealyticum%Drug resistance%Susceptibility test
目的：探讨解脲支原体对四环素类、喹诺酮类及大环内酯类药物的耐药情况。方法选择于2011年10月至2012年10月在我站治疗的解脲支原体阳性的泌尿生殖器感染患者75例，进行解脲支原体培养和药敏试验，观察解脲支原体的体外生长情况及其对抗生素的耐药情况。结果75例患者共进行1020孔药敏试验，其中耐药430孔，占42.1%，中敏及敏感590孔，57.8%，同一患者对2种以上药物耐药的有65例，占86.7%。10种被测试的抗生素的耐药率由高到低依次为环丙沙星、氧氟沙星、罗红霉素、阿奇霉素、司帕沙星、大观霉素、美满霉素、强力霉素、克拉霉素、交沙霉素。结论解脲支原体耐药发生率较高，且普遍存在多重耐药现象，临床用药应根据患者药敏情况来选择药物。
目的：探討解脲支原體對四環素類、喹諾酮類及大環內酯類藥物的耐藥情況。方法選擇于2011年10月至2012年10月在我站治療的解脲支原體暘性的泌尿生殖器感染患者75例，進行解脲支原體培養和藥敏試驗，觀察解脲支原體的體外生長情況及其對抗生素的耐藥情況。結果75例患者共進行1020孔藥敏試驗，其中耐藥430孔，佔42.1%，中敏及敏感590孔，57.8%，同一患者對2種以上藥物耐藥的有65例，佔86.7%。10種被測試的抗生素的耐藥率由高到低依次為環丙沙星、氧氟沙星、囉紅黴素、阿奇黴素、司帕沙星、大觀黴素、美滿黴素、彊力黴素、剋拉黴素、交沙黴素。結論解脲支原體耐藥髮生率較高，且普遍存在多重耐藥現象，臨床用藥應根據患者藥敏情況來選擇藥物。
목적：탐토해뇨지원체대사배소류、규낙동류급대배내지류약물적내약정황。방법선택우2011년10월지2012년10월재아참치료적해뇨지원체양성적비뇨생식기감염환자75례，진행해뇨지원체배양화약민시험，관찰해뇨지원체적체외생장정황급기대항생소적내약정황。결과75례환자공진행1020공약민시험，기중내약430공，점42.1%，중민급민감590공，57.8%，동일환자대2충이상약물내약적유65례，점86.7%。10충피측시적항생소적내약솔유고도저의차위배병사성、양불사성、라홍매소、아기매소、사파사성、대관매소、미만매소、강력매소、극랍매소、교사매소。결론해뇨지원체내약발생솔교고，차보편존재다중내약현상，림상용약응근거환자약민정황래선택약물。
Objective To investigate the drug resistance of ureaplasma urealyticum to tetracyclines, quinolones and macrolides. Methods Select 75 cases of urogenital infections with ureaplasma urealyticum infection positive, take ureaplasma urealyticum incubation experiment and susceptibility test, observe the in vitro growth and drug resistance of to antibiotics of ureaplasma urealyticum. Results Total 1020 susceptibility tests of 75 cases, 430 of resistance, 42.1%, 590 of moderately sensitive and sensitive, 57.8%, 65 cases got drug resistance to two or more types, 86.7%. From high to low, the resistance rates of 10 kinds of antibiotics to be tested were ciprolfoxacin, olfoxacin, roxithromycin, azithromycin, sparlfoxacin,spctinomycin, doxycycline, minocycline, clarithromycin, josamycin. Conclusion Ureaplasma urealyticum got a higher incidence of drug resistance, and multi-drug resistance phenomenon was widespread, clinical treatment should according to patient's drug sensitivity.
