国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2013年
12期
1068-1070
,共3页
穆艳顺%刘花玲%宋冬梅%张冬婕
穆豔順%劉花玲%宋鼕梅%張鼕婕
목염순%류화령%송동매%장동첩
茵栀黄%微生态制剂%新生儿%高胆红素血症
茵梔黃%微生態製劑%新生兒%高膽紅素血癥
인치황%미생태제제%신생인%고담홍소혈증
Yinzhi-huang%Probiotics%Neonatal%Hyperbilirubinemia
目的 探讨茵栀黄联合微生态制剂治疗新生儿高胆红素血症的疗效.方法 收集2010年5月至2012年8月华北石油管理局总医院儿科新生儿高胆红素血症患儿80例,采用随机数字表法将患儿随机分为两组各40例,对照组采用间隙蓝光照射,对胆红素上升快或水平高者给予纠酸、肝酶诱导剂、白蛋白静脉滴注等常规治疗方法.治疗组在对照组治疗基础上加用茵栀黄联合微生态制剂治疗.两组治疗前查血清总胆红素,治疗期间,应用经皮胆红素监测仪,监测每天胆红素变化,同时监测血清胆红素值下降至正常的时间.结果 治疗后治疗组日均胆红素下降值(53.07±17.80) μmol/L与对照组(30.56±13.43)μmol/L比较差异有统计学意义(P＜0.05);治疗组胆红素降至正常时间(4.87±2.06)d与对照组(7.12±2.33)d比较,差异均有统计学意义(P＜0.05);茵栀黄联合微生态制剂治疗组显效率75％ (30/40)明显高于对照组显效率35％ (14/40),两组显效率比较差异有统计学意义(x2=5.89,P＜0.05);茵栀黄联合微生态制剂治疗组总有效率92.5％ (37/40),明显高于对照组总有效率75％ (30/40),两组总有效率比较,差异有统计学意义(x2=4.50,P＜0.05).结论 茵栀黄联合微生态制剂治疗新生儿高胆红素血症日均胆红素下降值、血清胆红素值下降至正常的时间均优于常规治疗.
目的 探討茵梔黃聯閤微生態製劑治療新生兒高膽紅素血癥的療效.方法 收集2010年5月至2012年8月華北石油管理跼總醫院兒科新生兒高膽紅素血癥患兒80例,採用隨機數字錶法將患兒隨機分為兩組各40例,對照組採用間隙藍光照射,對膽紅素上升快或水平高者給予糾痠、肝酶誘導劑、白蛋白靜脈滴註等常規治療方法.治療組在對照組治療基礎上加用茵梔黃聯閤微生態製劑治療.兩組治療前查血清總膽紅素,治療期間,應用經皮膽紅素鑑測儀,鑑測每天膽紅素變化,同時鑑測血清膽紅素值下降至正常的時間.結果 治療後治療組日均膽紅素下降值(53.07±17.80) μmol/L與對照組(30.56±13.43)μmol/L比較差異有統計學意義(P＜0.05);治療組膽紅素降至正常時間(4.87±2.06)d與對照組(7.12±2.33)d比較,差異均有統計學意義(P＜0.05);茵梔黃聯閤微生態製劑治療組顯效率75％ (30/40)明顯高于對照組顯效率35％ (14/40),兩組顯效率比較差異有統計學意義(x2=5.89,P＜0.05);茵梔黃聯閤微生態製劑治療組總有效率92.5％ (37/40),明顯高于對照組總有效率75％ (30/40),兩組總有效率比較,差異有統計學意義(x2=4.50,P＜0.05).結論 茵梔黃聯閤微生態製劑治療新生兒高膽紅素血癥日均膽紅素下降值、血清膽紅素值下降至正常的時間均優于常規治療.
목적 탐토인치황연합미생태제제치료신생인고담홍소혈증적료효.방법 수집2010년5월지2012년8월화북석유관리국총의원인과신생인고담홍소혈증환인80례,채용수궤수자표법장환인수궤분위량조각40례,대조조채용간극람광조사,대담홍소상승쾌혹수평고자급여규산、간매유도제、백단백정맥적주등상규치료방법.치료조재대조조치료기출상가용인치황연합미생태제제치료.량조치료전사혈청총담홍소,치료기간,응용경피담홍소감측의,감측매천담홍소변화,동시감측혈청담홍소치하강지정상적시간.결과 치료후치료조일균담홍소하강치(53.07±17.80) μmol/L여대조조(30.56±13.43)μmol/L비교차이유통계학의의(P＜0.05);치료조담홍소강지정상시간(4.87±2.06)d여대조조(7.12±2.33)d비교,차이균유통계학의의(P＜0.05);인치황연합미생태제제치료조현효솔75％ (30/40)명현고우대조조현효솔35％ (14/40),량조현효솔비교차이유통계학의의(x2=5.89,P＜0.05);인치황연합미생태제제치료조총유효솔92.5％ (37/40),명현고우대조조총유효솔75％ (30/40),량조총유효솔비교,차이유통계학의의(x2=4.50,P＜0.05).결론 인치황연합미생태제제치료신생인고담홍소혈증일균담홍소하강치、혈청담홍소치하강지정상적시간균우우상규치료.
Objective To investigate the therapeutic efficacy of Yinzhi-huang combined with probiotics in the treatment of neonatal hyperbilirubinemia.Methods 80 neonates of hyperbilirubinemia were recruited into a treatment group (40 cases) and a control group (40 cases).The control group was treated with the gap blue light irradiation,besides,patients with rapid increase or high level of bilirubin were additionally treated with acid-correcting agents,Liver enzyme inducer,and albumin infusion; while the treatment group was additionally treated with Yinzhi-huang and probiotics on the basis of the control group.The values of serum total bilirubin before the treatment Was determined in both groups.During treatment,the changes of daily bilirubin,were monitored with percutaneous bilirubin monitor,and the time for serum bilirubin values decreased to normal level was studied in both groups.Results The two groups showed no significant difference in examination of the serum bilirubin values before treatment(P＞0.05).The daily bilirubin decreased value of treatment group(53.07± 17.80) μmol/L showed statistically significant compared with the control group(30.56± 13.43)μmol/L(P＜0.05); the time for serum bilirubin values decreased to normal level in the treatment group (4.87± 2.06) d was significantly different compared with the control group (7.12± 2.33) d,(P＜ 0.05).The apparent effective rate in the treatment group 75％ (30/40) was higher than that in the control group 35％(14/40)with statistical significance(x2=5.89,P＜0.05).The total effective rate in the treatment group 92.5％ (37/40)was higher than the control group 75％ (30/40)with statistical significance (x2=4.50,P＜0.05).Conclusion Yinzhi-huang combined with probiotics has better effects than conventional treatment in decreasing the daily bilirubin values,restoring normal serum bilirubin time of neonatal hyperbilirubinemia and it is worthy of clinical application.
