中国医药
中國醫藥
중국의약
CHINA MEDICINE
2014年
1期
106-108
,共3页
郭丽明%丛品%沈强%谢晓兴%徐锦
郭麗明%叢品%瀋彊%謝曉興%徐錦
곽려명%총품%침강%사효흥%서금
咽喉反流病%雷贝拉唑%柴胡疏肝散
嚥喉反流病%雷貝拉唑%柴鬍疏肝散
인후반류병%뢰패랍서%시호소간산
Pharyngeal reflux disease%Rabeprazole%Bupleurum liver-coursing decoction
目的 观察雷贝拉唑联合柴胡疏肝散治疗咽喉反流病的临床效果.方法 选取2010年1月至2012年12月于浙江中医药大学附属同德医院接受治疗的咽喉反流病患者110例,完全随机分为对照组和观察组,每组55例.对照组给予雷贝拉唑治疗,每次10 mg,每日早、晚餐前30 min口服;观察组在对照组基础上加用柴胡疏肝散,每日1剂,水煎服,分2次服用.观察比较2组患者治疗前后的内窥镜检查评分及临床效果.结果 2组治疗后内窥镜检查评分与治疗前比较[观察组:(0.2±0.1)分比(1.5±0.6)分;对照组:(0.3±0.1)分比(1.5±0.7)分],差异均有统计学意义(均P＜O.05).治疗后,观察组内窥镜检查评分明显低于对照组,差异有统计学意义(P＜0.05).对照组总有效率为70.9％(39/55),明显低于观察组的90.9％(50/55),差异有统计学意义(P＜0.05).结论 采用雷贝拉唑联合柴胡疏肝散治疗咽喉反流病临床效果明显.
目的 觀察雷貝拉唑聯閤柴鬍疏肝散治療嚥喉反流病的臨床效果.方法 選取2010年1月至2012年12月于浙江中醫藥大學附屬同德醫院接受治療的嚥喉反流病患者110例,完全隨機分為對照組和觀察組,每組55例.對照組給予雷貝拉唑治療,每次10 mg,每日早、晚餐前30 min口服;觀察組在對照組基礎上加用柴鬍疏肝散,每日1劑,水煎服,分2次服用.觀察比較2組患者治療前後的內窺鏡檢查評分及臨床效果.結果 2組治療後內窺鏡檢查評分與治療前比較[觀察組:(0.2±0.1)分比(1.5±0.6)分;對照組:(0.3±0.1)分比(1.5±0.7)分],差異均有統計學意義(均P＜O.05).治療後,觀察組內窺鏡檢查評分明顯低于對照組,差異有統計學意義(P＜0.05).對照組總有效率為70.9％(39/55),明顯低于觀察組的90.9％(50/55),差異有統計學意義(P＜0.05).結論 採用雷貝拉唑聯閤柴鬍疏肝散治療嚥喉反流病臨床效果明顯.
목적 관찰뢰패랍서연합시호소간산치료인후반류병적림상효과.방법 선취2010년1월지2012년12월우절강중의약대학부속동덕의원접수치료적인후반류병환자110례,완전수궤분위대조조화관찰조,매조55례.대조조급여뢰패랍서치료,매차10 mg,매일조、만찬전30 min구복;관찰조재대조조기출상가용시호소간산,매일1제,수전복,분2차복용.관찰비교2조환자치료전후적내규경검사평분급림상효과.결과 2조치료후내규경검사평분여치료전비교[관찰조:(0.2±0.1)분비(1.5±0.6)분;대조조:(0.3±0.1)분비(1.5±0.7)분],차이균유통계학의의(균P＜O.05).치료후,관찰조내규경검사평분명현저우대조조,차이유통계학의의(P＜0.05).대조조총유효솔위70.9％(39/55),명현저우관찰조적90.9％(50/55),차이유통계학의의(P＜0.05).결론 채용뢰패랍서연합시호소간산치료인후반류병림상효과명현.
Objective To observe the clinical effect of rabeprazole thiazole combined with Bupleurum Liver-Coursing Decoction on pharyngeal reflux disease.Methods All 110 patients with pharyngeal reflux disease in Tongde hospital of Zhejiang province from January 2010 to December 2012 were selected and randomly divided into control group (55 cases) and observation group (55 cases).The control group was given rabeprazole thiazole and the observation group was given rabeprazole thiazole combined with Bupleurum liver-coursing decoction.Endoscopy results and clinical effect of two groups were observed and compared.Results There were significant differences on endoscopy results of two groups after treatment compared with before treatment [observation group:(0.2 ± 0.1) scores vs (1.5 ± 0.6) scores ; control group:(0.3 ± 0.1) scores vs (1.5 ± 0.7) scores] (P ＜ 0.05).There were significant differences on endoscopy results of observation group after treatment compared with control group (P ＜ 0.05).The total effect rate of control group was 70.9％ (39/55),which was significantly lower than that of observation group 90.9％ (50/55) (P ＜ 0.05).Conclusion Rabeprazole combined with Bupleurum liver-coursing Decoction has a good clinical effect on the treatment of pharyngeal reflux disease.
