食品与药品
食品與藥品
식품여약품
FOOD AND DRUG
2013年
4期
288-290,291
,共4页
H7N9禽流感病毒%H7亚型致命力机制%抗病毒药物
H7N9禽流感病毒%H7亞型緻命力機製%抗病毒藥物
H7N9금류감병독%H7아형치명력궤제%항병독약물
H7N9 AIV%mechanism of pathogenicity of H7 subtype%antiviral drugs
1997年发现H5N1禽流感病毒（H5N1 AIV）跨越物种障碍使人感染，致死率60%，表明H5N1是一强致病力的流感病毒。H7N9禽流感病毒是2013年3月在我国上海和安徽发现并感染人的一种新的禽流感病毒株。我国立即采取了重大措施加以控制。H7N9禽流感的出现受到了世界许多国家和世界卫生组织的严重关注。本文介绍了禽流感病毒的分类和命名法，及以往H7禽流感的流行和人感染病例，讨论了H7亚型致病力的机制，综述了H7N9流感病毒及抗病毒药物研究进展，为H7N9禽流感的预防、治疗的研究和新药开发提供有益的参考。
1997年髮現H5N1禽流感病毒（H5N1 AIV）跨越物種障礙使人感染，緻死率60%，錶明H5N1是一彊緻病力的流感病毒。H7N9禽流感病毒是2013年3月在我國上海和安徽髮現併感染人的一種新的禽流感病毒株。我國立即採取瞭重大措施加以控製。H7N9禽流感的齣現受到瞭世界許多國傢和世界衛生組織的嚴重關註。本文介紹瞭禽流感病毒的分類和命名法，及以往H7禽流感的流行和人感染病例，討論瞭H7亞型緻病力的機製，綜述瞭H7N9流感病毒及抗病毒藥物研究進展，為H7N9禽流感的預防、治療的研究和新藥開髮提供有益的參攷。
1997년발현H5N1금류감병독（H5N1 AIV）과월물충장애사인감염，치사솔60%，표명H5N1시일강치병력적류감병독。H7N9금류감병독시2013년3월재아국상해화안휘발현병감염인적일충신적금류감병독주。아국립즉채취료중대조시가이공제。H7N9금류감적출현수도료세계허다국가화세계위생조직적엄중관주。본문개소료금류감병독적분류화명명법，급이왕H7금류감적류행화인감염병례，토론료H7아형치병력적궤제，종술료H7N9류감병독급항병독약물연구진전，위H7N9금류감적예방、치료적연구화신약개발제공유익적삼고。
In 1997, it was found that H5N1 avian influenza virus (H5N1 AIV) could infect human beings over the species barrier. The people infected by H5N1 show a high death rate(60 %).So that H5N1 is a virus with strong pathogenicity. H7N9 AIV is a novel strain of H7 virus which was found in March, 2013 in Shanghai and Anhui of China and infected to human. Chinese Government has adopted important measures to control it. The appearance of H7N9 avian influenza brings about a serious attention by many countries in the world and World Health Organization. In this paper, the classification and nomenclature of AIV, the spread of H7 and the cases of human infected by H7 in past time are introduced. The mechanism of pathogenicity of H7 subtype is discussed. Progress on H7N9 AIV and antiviral drugs are reviewed. It will be a beneficial reference for the studies of prevention, therapeutics of H7N9 avian influenza and development of new antiviral drugs.
