食品与药品
食品與藥品
식품여약품
FOOD AND DRUG
2013年
4期
277-279,280
,共4页
聂延君%单红宾%张雷%刘琦%谢元超
聶延君%單紅賓%張雷%劉琦%謝元超
섭연군%단홍빈%장뢰%류기%사원초
橘红丸%自身对照法%溶出度%紫外分光光度法%中药制剂
橘紅汍%自身對照法%溶齣度%紫外分光光度法%中藥製劑
귤홍환%자신대조법%용출도%자외분광광도법%중약제제
Juhong Pills%self-control method%dissolution%UV spectrophotometry%traditional Chinese medicine preparations
目的建立自身对照法测定橘红丸溶出度。方法采用自身对照法（UV）测定橘红丸的溶出度。采用篮法，溶出介质为0.1 mol/L的盐酸溶液（900 mL），转速150 r/min，取样时间120 min。结果橘红丸溶出度测定自身对照法在相当于柚皮苷0.1~1.1μg/mL浓度范围内呈线性( r=0.9999， n=6)，平均回收率为101.26%，RSD为2.38%。结论本法简便、准确、可行，可作为橘红丸的质量标准中控制项目之一。
目的建立自身對照法測定橘紅汍溶齣度。方法採用自身對照法（UV）測定橘紅汍的溶齣度。採用籃法，溶齣介質為0.1 mol/L的鹽痠溶液（900 mL），轉速150 r/min，取樣時間120 min。結果橘紅汍溶齣度測定自身對照法在相噹于柚皮苷0.1~1.1μg/mL濃度範圍內呈線性( r=0.9999， n=6)，平均迴收率為101.26%，RSD為2.38%。結論本法簡便、準確、可行，可作為橘紅汍的質量標準中控製項目之一。
목적건립자신대조법측정귤홍환용출도。방법채용자신대조법（UV）측정귤홍환적용출도。채용람법，용출개질위0.1 mol/L적염산용액（900 mL），전속150 r/min，취양시간120 min。결과귤홍환용출도측정자신대조법재상당우유피감0.1~1.1μg/mL농도범위내정선성( r=0.9999， n=6)，평균회수솔위101.26%，RSD위2.38%。결론본법간편、준학、가행，가작위귤홍환적질량표준중공제항목지일。
Objective To establish the self-control method for determination of dissolution of Juhong Pills. Methods UV spectrophotometry was applied to determine the dissolution of Juhong Pills. Basket apparatus was used, with 0.1 mol/L hydrochloric acid as the dissolution medium. The rotation speed was 150 r/min and dissolution time limit was 120 min. Results The linear range of the method was 0.1~1.1μg/mL(equivalent to the concentration of naringin), r=0.9999. The average recovery was 101.26%, RSD was 2.38%. Conclusion This method is convenient, accurate and feasible. It can be applied to determine dissolution of Juhong Pills.
