CAJ | 학술논문

　　间充质干细胞向肝细胞诱导分化成功后，分化后的肝细胞样细胞应用于肝病成为了研究热点。不仅未分化的间充质干细胞能治疗肝病，其来源的分化后的肝细胞样细胞亦能有效治疗肝病。因此，有必要对间充质干细胞分化前后的细胞治疗效果进行比较评价。本文从诱导分化培养方案、鉴定指标及相关细胞生物学功能进行述评。
　　간충질간세포향간세포유도분화성공후，분화후적간세포양세포응용우간병성위료연구열점。불부미분화적간충질간세포능치료간병，기래원적분화후적간세포양세포역능유효치료간병。인차，유필요대간충질간세포분화전후적세포치료효과진행비교평개。본문종유도분화배양방안、감정지표급상관세포생물학공능진행술평。
The protocols for differentiation of hepatocyte-like cells (HLCs) from mesenchymal stem cells (MSCs) have been well established. Previous datas have shown that MSCs and their derived-HLCs were able to engraft injured liver and alleviate injuries. It is necessary to elvaluate the cells therapeutic effects before and after MSCs differentiation. We will make a brief comment on the induction and differentiation culture protocol, hepatic markers and related functions of cell biology.