实用放射学杂志
實用放射學雜誌
실용방사학잡지
JOURNAL OF PRACTICAL RADIOLOGY
2014年
5期
795-798
,共4页
侯炜寰%任静%潘奇%李娜%刘会佳%黄旭方%张振华%芦军涛%印弘%宦怡
侯煒寰%任靜%潘奇%李娜%劉會佳%黃旭方%張振華%蘆軍濤%印弘%宦怡
후위환%임정%반기%리나%류회가%황욱방%장진화%호군도%인홍%환이
直肠癌%扩散加权成像%表观扩散系数%预后
直腸癌%擴散加權成像%錶觀擴散繫數%預後
직장암%확산가권성상%표관확산계수%예후
rectal cancer%diffusion-weighted imaging%apparent diffusion coefficient%prognosis
目的：探讨表观扩散系数(apparent diffusion coefficient,ADC)对直肠癌临床病理及预后的评估价值。方法回顾性分析109例经手术病理证实为直肠癌患者的 MRI 及 DWI 资料,ADC 值由 b 值为0 s/mm2与1000 s/mm2的 DWI 检查所获取,测量肿瘤平均 ADC 值,根据肿瘤分化程度、T 分期以及直肠系膜筋膜、脉管和神经是否受侵犯进行分组分析。结果直肠癌平均 ADC值在肿瘤分化程度组、T 分期组、N 分期组以及直肠系膜筋膜和神经是否受犯侵组的差异有统计学意义,多重比较显示肿瘤分化程度组的高-中分化与中分化(P =0.996)、中-低分化与低分化(P =0.957)的平均 ADC 值无统计学意义,其余之间差异均有统计学意义(P <0.05)；T 分期组中 T1与 T3期的平均 ADC 值有统计学意义(P <0.05),其余均无统计学意义(P >0.05)；N 分期组的 N0、N1和 N2期3组平均 ADC 值间均无统计学意义(P >0.05)。结论 ADC 值可在一定程度上反映直肠癌的病理分级及预后。
目的：探討錶觀擴散繫數(apparent diffusion coefficient,ADC)對直腸癌臨床病理及預後的評估價值。方法迴顧性分析109例經手術病理證實為直腸癌患者的 MRI 及 DWI 資料,ADC 值由 b 值為0 s/mm2與1000 s/mm2的 DWI 檢查所穫取,測量腫瘤平均 ADC 值,根據腫瘤分化程度、T 分期以及直腸繫膜觔膜、脈管和神經是否受侵犯進行分組分析。結果直腸癌平均 ADC值在腫瘤分化程度組、T 分期組、N 分期組以及直腸繫膜觔膜和神經是否受犯侵組的差異有統計學意義,多重比較顯示腫瘤分化程度組的高-中分化與中分化(P =0.996)、中-低分化與低分化(P =0.957)的平均 ADC 值無統計學意義,其餘之間差異均有統計學意義(P <0.05)；T 分期組中 T1與 T3期的平均 ADC 值有統計學意義(P <0.05),其餘均無統計學意義(P >0.05)；N 分期組的 N0、N1和 N2期3組平均 ADC 值間均無統計學意義(P >0.05)。結論 ADC 值可在一定程度上反映直腸癌的病理分級及預後。
목적：탐토표관확산계수(apparent diffusion coefficient,ADC)대직장암림상병리급예후적평고개치。방법회고성분석109례경수술병리증실위직장암환자적 MRI 급 DWI 자료,ADC 치유 b 치위0 s/mm2여1000 s/mm2적 DWI 검사소획취,측량종류평균 ADC 치,근거종류분화정도、T 분기이급직장계막근막、맥관화신경시부수침범진행분조분석。결과직장암평균 ADC치재종류분화정도조、T 분기조、N 분기조이급직장계막근막화신경시부수범침조적차이유통계학의의,다중비교현시종류분화정도조적고-중분화여중분화(P =0.996)、중-저분화여저분화(P =0.957)적평균 ADC 치무통계학의의,기여지간차이균유통계학의의(P <0.05)；T 분기조중 T1여 T3기적평균 ADC 치유통계학의의(P <0.05),기여균무통계학의의(P >0.05)；N 분기조적 N0、N1화 N2기3조평균 ADC 치간균무통계학의의(P >0.05)。결론 ADC 치가재일정정도상반영직장암적병리분급급예후。
Objective To assess the value of apparent diffusion coefficient (ADC)in clinic ,pathology and prognosis of rectal cancer. Methods The MRI and DWI findings of 109 patients with pathological proved rectal adenocarcinoma were retrospectively analyzed. DWI with b=0 s/mm2 and b= 1 000 s/mm2 were acquired.Mean tumor ADCs were measured and compared between subgroups stratified by histologic differentiation grades,T-stage,N-stage,mesorectal fascia status and presence of lymphangiovascular or peri-neral invasion.Results Mean tumor ADCs were significantly different when comparing groups stratified by histologic differentiation grades,T-stage,mesorectal fascia status and presence of lymphangiovascular invasion.Tukey’s post hoc test showed that the differences of mean ADCs between good-moderate differentiated group and moderate differentiated group(P =0.996),moderate-poor differentiated group and poor differentiated group(P =0.957)were not significant.The differences among other groups of differentia-tion grades differed significantly(P <0.05).In the T-stage groups,the mean ADCs of T1 stage tumor was significantly higher than that of T3 stage tumor(P <0.05).There were no significant differences among other T-stage groups(P >0.05).There were no sig-nificant differences among N0,N1 and N2 in N-stage groups(P >0.05).Conclusion ADC values can reflect pathologic and prognos-tic features of rectal cancer.
