中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
3期
109-110
,共2页
病毒性脑炎%更昔洛韦%阿昔洛韦%疗效
病毒性腦炎%更昔洛韋%阿昔洛韋%療效
병독성뇌염%경석락위%아석락위%료효
Virus encephalitis%Ganciclovir%Acyclovir%Curative effect
目的：探讨更昔洛韦治疗成人病毒性脑炎的临床疗效。方法：60例患者按随机数字表法分为观察组和对照组，每组各30例，分别采用更昔洛韦和阿昔洛韦治疗，比较两组疗效和症状改善时间。结果：经治疗后，观察组有效率为93.33%，对照组为76.67%，观察组疗效优于对照组，差异有统计学意义（Ridit z=24.626，P=0.000）；观察组在发热、意识障碍、惊厥、头痛、精神症状和脑电图改善上时间均短于对照组，差异有统计学意义（P<0.05）。结论：与阿昔洛韦相比，更昔洛韦起效快，疗效高，值得临床推广应用。
目的：探討更昔洛韋治療成人病毒性腦炎的臨床療效。方法：60例患者按隨機數字錶法分為觀察組和對照組，每組各30例，分彆採用更昔洛韋和阿昔洛韋治療，比較兩組療效和癥狀改善時間。結果：經治療後，觀察組有效率為93.33%，對照組為76.67%，觀察組療效優于對照組，差異有統計學意義（Ridit z=24.626，P=0.000）；觀察組在髮熱、意識障礙、驚厥、頭痛、精神癥狀和腦電圖改善上時間均短于對照組，差異有統計學意義（P<0.05）。結論：與阿昔洛韋相比，更昔洛韋起效快，療效高，值得臨床推廣應用。
목적：탐토경석락위치료성인병독성뇌염적림상료효。방법：60례환자안수궤수자표법분위관찰조화대조조，매조각30례，분별채용경석락위화아석락위치료，비교량조료효화증상개선시간。결과：경치료후，관찰조유효솔위93.33%，대조조위76.67%，관찰조료효우우대조조，차이유통계학의의（Ridit z=24.626，P=0.000）；관찰조재발열、의식장애、량궐、두통、정신증상화뇌전도개선상시간균단우대조조，차이유통계학의의（P<0.05）。결론：여아석락위상비，경석락위기효쾌，료효고，치득림상추엄응용。
Objective:To explore the clinical effect of ganciclovir in the treatment of adult viral encephalitis.Method:60 patients were randomly divided into the observation group and the control group according to random number table method,each group had 30 cases,used ganciclovir and acyclovir to treat respectively,compared the curative effect and symptom improvement time of two groups.Result:After treatment,the efficiency of the observation group was 93.33%,and 76.67%in the control group,the control group curative effect was better than the observation group,there was statistically significant differences in the efficacy of the two groups(Ridit z=24.626,P=0.000);the time in fever,disturbance of consciousness, headache,seizures,mental symptoms and EEG improvement were shorter than the control group,there were statistical significant differences(P<0.05). Conclusion:Compare with acyclovir,ganciclovir with faster acting,high curative effect,worthy of clinical application. Worthy of clinical application.
