CAJ | 학술논문

　　试验研究了不同质量浓度下(5、20、50 mg/L)三组柴油分散液，对马粪海胆的肠体、性腺、体液三个部位的抗氧化还原系统细胞色素P450活性变化的影响。结果表明，随着污染暴露时间的增加，三个部位的细胞色素P450活性均呈现出先被诱导、后被抑制的规律，并且油浓度越高，出现诱导和抑制效应的时间越早，活性变化的幅度也越大。海胆P450活性变化在一定程度上能够反映油污染的强度及其对海洋生物的毒性效应，可作为海洋石油烃污染监测的毒理学指标。
　　시험연구료불동질량농도하(5、20、50 mg/L)삼조시유분산액，대마분해담적장체、성선、체액삼개부위적항양화환원계통세포색소P450활성변화적영향。결과표명，수착오염폭로시간적증가，삼개부위적세포색소P450활성균정현출선피유도、후피억제적규률，병차유농도월고，출현유도화억제효응적시간월조，활성변화적폭도야월대。해담P450활성변화재일정정도상능구반영유오염적강도급기대해양생물적독성효응，가작위해양석유경오염감측적독이학지표。
In this paper, the effects of different concentrations of diesel(5, 20 and 50 mg/L)on the activities of cy-tochrome P450 in the intestine, coelomic fluid and gonad of Hemicentrotus pulcherrimus were studied. The results showed that the P450 activities were induced at first and then inhibited with the increase of diesel concentration and exposure time. And the higher the oil concentration is, the earlier the induced and inhibited time occurred, and more significantly the P450 activities changed. Therefore the P450 activity of Hemicentrotus pulcherrimus was a suitable biomarker to mornitor the marine oil pollution since it may somewhat reflect the toxical effects of oil hydrocarbon on marine organisms.