CAJ | 학술논문

目的：研究老老年高血压患者血压昼夜节律与红细胞分布宽度变异系数(RDW cv)的相关性。方法选择2011年4月-2013年4月入住中国中医科学院广安门医院138例老老年高血压患者,分成 RDW cv正常组和升高组,比较两组间各相关理化指标的情况。将患者分成杓型血压组和非杓型血压组,比较两组患者 RDW cv的情况。结果 RDW cv正常组和异常组比较,24 h平均舒张压、平均动脉压、夜间血压下降率、高密度脂蛋白(HDL C)差异有统计学意义(P<0.05)；非杓型组RDW cv高于杓型组(P<0.05)。经相关性分析结果显示,血压昼夜节律与 RDW cv存在显著相关性(P=0.012)；多元线性逐步回归分析显示,高密度脂蛋白、夜间血压下降率是 RDW cv的影响因素。结论老老年高血压患者的血压昼夜节律、高密度脂蛋白与 RDW cv 之间关系密切,RDW cv或许可以成为预测老老年高血压患者预后的危险因素之一。
목적：연구로노년고혈압환자혈압주야절률여홍세포분포관도변이계수(RDW cv)적상관성。방법선택2011년4월-2013년4월입주중국중의과학원엄안문의원138례로노년고혈압환자,분성 RDW cv정상조화승고조,비교량조간각상관이화지표적정황。장환자분성표형혈압조화비표형혈압조,비교량조환자 RDW cv적정황。결과 RDW cv정상조화이상조비교,24 h평균서장압、평균동맥압、야간혈압하강솔、고밀도지단백(HDL C)차이유통계학의의(P<0.05)；비표형조RDW cv고우표형조(P<0.05)。경상관성분석결과현시,혈압주야절률여 RDW cv존재현저상관성(P=0.012)；다원선성축보회귀분석현시,고밀도지단백、야간혈압하강솔시 RDW cv적영향인소。결론로노년고혈압환자적혈압주야절률、고밀도지단백여 RDW cv 지간관계밀절,RDW cv혹허가이성위예측로노년고혈압환자예후적위험인소지일。
Objective To study the correlation between circadian rhythm of blood pressure and red distribution width coefficient variation (RDW cv).Methods One hundred and thirty eight elderly with hypertension patients were divided into RDW cv normal group,and elevated group.The physicochemical index was compared.Then patients were divided into dipper hypertension subgroup and non dipper blood pressure subgroup,RDW cv was compared in two groups.Results The 24 hours average diastolic blood pres-sure,mean arterial pressure,nocturnal blood pressure decline rate,and HDL C in normal and abnormal RDW cv group had signifi-cant difference (P<0.05).RDW cv was higher in non dipper group than dipper group (P<0.05).The Pearson correlation analysis showed,there was significant correlation between blood pressure circadian rhythm and RDW cv (P=0.012).Multiple linear step-wise regression analysis showed:High density lipoprotein,nocturnal blood pressure decline rate was the influencing factors of RDW cv. Conclusion The blood pressure circadian rhythm and high density lipoprotein in very elderly hypertension patients correlated with RDW cv.RDW cv might be one of the risk factors in predicting the prognosis of very elderly hypertensive patients.