CAJ | 학술논문

目的探讨甲状腺球蛋白(Tg)测定与131碘全身扫描(WBS)对分化型甲状腺癌(DTC)131碘治疗后的随访价值.方法对164例DTCTC131碘治疗后,采用Tg测定与131碘全身扫描作为随访方法,观察DTC复发或转移情况.结果血清Tg测定与131碘WBS对DTC复发或转移诊断有高度的一致性(kappa值0.587,SE=0.076,P＜0.01),但会出现假阴性.结论在DTC131碘治疗后进行随访的过程中,测定血清Tg时必须同时做血清TgAb测定,以防假阴性出现.
목적 탐토갑상선구단백(Tg)측정여131전전신소묘(WBS)대분화형갑상선암(DTC)131전치료후적수방개치.방법 대164례DTCTC131전치료후,채용Tg측정여131전전신소묘작위수방방법,관찰DTC복발혹전이정황.결과 혈청Tg측정여131전WBS대DTC복발혹전이진단유고도적일치성(kappa치0.587,SE=0.076,P＜0.01),단회출현가음성.결론 재DTC131전치료후진행수방적과정중,측정혈청Tg시필수동시주혈청TgAb측정,이방가음성출현.
Objective To explore the value of follow-up of serum TSH stimulating thyroglobulin (Tg) test and 131I whole body scan(WBS) in patients with differentiated thyroid cancer(DTC) who were treated by 131I.Methods By SPSS software,Kappa test was performed between results of serum Tg,TgAb test and WBS for diagnosis of persistent/recurrent DTC.Results Consistency test of TSH stimulating Tg,TgAb and 131I WBS for diagnostic persistent/recurrent or metastasis of DTC:kappa value =0.587,SE =0.076,P ＜ 0.01.Although the results showed that two measurements appeared definite consistency,it is dissatisfactory.Conclusion Serum TSH stimulating Tg test and 131I whole body scan(WBS) are important follow-up tools for patients with DTC.Because of Tg interfering it is necessary to performed TgAb test simultaneously,when Tg test was performed.Especially 131I WBS do is not absent because false negative would be able to appeared in single serum TSH stimulating Tg and TgAb test.