CAJ | 학술논문

目的：探讨帕瑞昔布钠超前镇痛对老年腹部手术患者术后镇痛效果的影响。方法选取ASA I-II级行开腹手术治疗老年患者60例，随机分为观察组和对照组，每组30例。观察组患者麻醉开始前30 min静脉注射帕瑞昔布钠40 mg，对照组在同一时间静脉注射等量生理盐水。结果比较两组患者术后镇痛效果视觉模拟评分（VAS）及VAS改善幅度，观察组明显优于对照组；观察组患者恶心、嗜睡、头晕发生率明显低于对照组；观察组患者使用术后补救镇痛药物数量减少。结论帕瑞昔布钠超前镇痛对于老年腹部手术患者术后镇痛效果较好，安全性较高。
목적：탐토파서석포납초전진통대노년복부수술환자술후진통효과적영향。방법선취ASA I-II급행개복수술치료노년환자60례，수궤분위관찰조화대조조，매조30례。관찰조환자마취개시전30 min정맥주사파서석포납40 mg，대조조재동일시간정맥주사등량생리염수。결과비교량조환자술후진통효과시각모의평분（VAS）급VAS개선폭도，관찰조명현우우대조조；관찰조환자악심、기수、두훈발생솔명현저우대조조；관찰조환자사용술후보구진통약물수량감소。결론파서석포납초전진통대우노년복부수술환자술후진통효과교호，안전성교고。
Objective To investigate parecoxib sodium preemptive analgesia effects of abdominal surgery in elderly patients with postoperative analgesia. Methods ASA I-II class underwent open surgery. 60 cases of elderly patients were randomly divided into observation group and control group, 30 cases in each group. The observation group started 30 min before anesthesia intravenously parecoxib sodium 40 mg, control group at the same time intravenous Saline. Results The postoperative analgesia magnitude improvement in VAS score and VAS was significantly better than the control group; observation group were nausea, sleepiness, dizziness was significantly lower than the control group; patients using the drug reduced postoperative pain remedy were observed. Conclusion Parecoxib sodium preemptive analgesia for postoperative analgesia in elderly patients with abdominal surgery is better, higher security method in relieving pains in clinical practices.