中华普通外科学文献（电子版）
中華普通外科學文獻（電子版）
중화보통외과학문헌（전자판）
CHINESE JOURNAL OF GENERAL SURGERY(ELECTRONIC VERSION)
2014年
3期
209-212
,共4页
胃癌%预后%影响因素%COX模型
胃癌%預後%影響因素%COX模型
위암%예후%영향인소%COX모형
Gastric carcinoma%Prognosis%Influence factors%Cox model
目的：探讨影响胃癌预后的主要因素。方法选择中山市人民医院普外三科2005年12月至2008年12月收治的160例胃癌患者，采用COX回归模型，将患者的临床资料和随访情况作为分析因子计算生存率，多因素回归分析预后影响因素。结果总随访率93.75%（150/160），截至2013年1月存活53例，总1、3、5年累计生存率分别为66.70%、50.67%、38.67%。单因素分析表明胃癌预后与手术方式、肿瘤大体分型、组织分型、浸润深度、淋巴结转移情况及TNM分期有关（P<0.05）。COX多因素分析结果显示手术方式、肿瘤大体分型、组织分型、浸润深度、淋巴结转移情况及TNM分期是胃癌预后的独立预后因素（P<0.05）。Borrmman分型与远期预后相关，而与近期预后无关。综合治疗与近期预后有关，与远期预后无关。结论手术方式、肿瘤大体分型、组织分型、浸润深度、淋巴结转移情况及TNM分期是胃癌预后的独立预后因素。
目的：探討影響胃癌預後的主要因素。方法選擇中山市人民醫院普外三科2005年12月至2008年12月收治的160例胃癌患者，採用COX迴歸模型，將患者的臨床資料和隨訪情況作為分析因子計算生存率，多因素迴歸分析預後影響因素。結果總隨訪率93.75%（150/160），截至2013年1月存活53例，總1、3、5年纍計生存率分彆為66.70%、50.67%、38.67%。單因素分析錶明胃癌預後與手術方式、腫瘤大體分型、組織分型、浸潤深度、淋巴結轉移情況及TNM分期有關（P<0.05）。COX多因素分析結果顯示手術方式、腫瘤大體分型、組織分型、浸潤深度、淋巴結轉移情況及TNM分期是胃癌預後的獨立預後因素（P<0.05）。Borrmman分型與遠期預後相關，而與近期預後無關。綜閤治療與近期預後有關，與遠期預後無關。結論手術方式、腫瘤大體分型、組織分型、浸潤深度、淋巴結轉移情況及TNM分期是胃癌預後的獨立預後因素。
목적：탐토영향위암예후적주요인소。방법선택중산시인민의원보외삼과2005년12월지2008년12월수치적160례위암환자，채용COX회귀모형，장환자적림상자료화수방정황작위분석인자계산생존솔，다인소회귀분석예후영향인소。결과총수방솔93.75%（150/160），절지2013년1월존활53례，총1、3、5년루계생존솔분별위66.70%、50.67%、38.67%。단인소분석표명위암예후여수술방식、종류대체분형、조직분형、침윤심도、림파결전이정황급TNM분기유관（P<0.05）。COX다인소분석결과현시수술방식、종류대체분형、조직분형、침윤심도、림파결전이정황급TNM분기시위암예후적독립예후인소（P<0.05）。Borrmman분형여원기예후상관，이여근기예후무관。종합치료여근기예후유관，여원기예후무관。결론수술방식、종류대체분형、조직분형、침윤심도、림파결전이정황급TNM분기시위암예후적독립예후인소。
Objective To investigate the major influences of the gastric cancer prognosis. Methods Prognostic factors of the gastric cancer were analyzed by Cox multivariate regression model based on clinical data of 160 cases with gastric cancer in the Third Department of General Surgery of Zhongshan City People's Hospital from December 2005 to December 2008. And the survival rates were calculated. Results Until January 2013, 150 cases (93.75%) were followed up with 53 survived, the overall survival rate for 1-, 3-, 5-year was 66.70%, 50.67%, 38.67%respectively. Univariate analysis indicated that the operation type, tumor gross subtypes, histological subtypes, invasion depth, lymph node metastasis and TNM stage were found to be significantly associated with the prognosis of the gastric cancer (P<0.05). Cox multivariate analysis illustrated the operation type, tumor gross subtypes, histological subtypes, invasion depth, lymph node metastasis and TNM stage were the major independent prognostic factors (P<0.05). The Borrmman subtypes were related with long term prognosis, while not related with short term prognosis. The combined therapy strategy was related with short term prognosis, while not related with long term prognosis. Conclusion Operation type, tumor gross subtypes, histological subtypes, invasion depth, lymph node metastasis and TNM stage are the major independent prognostic factors for gastric cancer.
