CAJ | 학술논문

目的：探讨补充维生素B对老年性阴道炎临床疗效及预后的影响。方法以老年性阴道炎患者为研究对象，随机分成观察组和对照组。两组均给予复方甲硝唑栓和雌三醇乳膏治疗2周，观察组在上述基础上给予复方维生素 B片（用法：前2周2片/次，3次/d；其后改为1片/次，1次/d，连用1个月）治疗。比较两组临床疗效、症状体征及复发情况。结果①观察组总有效率（93．55％）略高于对照组（88．71％），但差异无统计学意义（P＞0．05）；②2组治疗后分泌物增多、阴道瘙痒、阴道灼热、阴道壁充血及分泌物镜检清洁度均较治疗前显著改善，差异均有统计学意义（P＜0．01）；③观察组复发率（24．24％）显著低于对照组（60．00％），差异有统计学意义（P＜0．01）。结论维生素B可改善老年性阴道炎患者的症状，降低复发率。
목적：탐토보충유생소B대노년성음도염림상료효급예후적영향。방법이노년성음도염환자위연구대상，수궤분성관찰조화대조조。량조균급여복방갑초서전화자삼순유고치료2주，관찰조재상술기출상급여복방유생소 B편（용법：전2주2편/차，3차/d；기후개위1편/차，1차/d，련용1개월）치료。비교량조림상료효、증상체정급복발정황。결과①관찰조총유효솔（93．55％）략고우대조조（88．71％），단차이무통계학의의（P＞0．05）；②2조치료후분비물증다、음도소양、음도작열、음도벽충혈급분비물경검청길도균교치료전현저개선，차이균유통계학의의（P＜0．01）；③관찰조복발솔（24．24％）현저저우대조조（60．00％），차이유통계학의의（P＜0．01）。결론유생소B가개선노년성음도염환자적증상，강저복발솔。
Objective To explore the effect of vitamin B on the treatment of senile vaginitis .Methods A total of 124 pa-tients suffered senile vaginitis were included in the study , who were accepted the treatment of compound metronidazole suppositories and estriol cream.By simple randomization,the patients accepted the treatment of vitamin B were divided into the observe group and control group.The difference of the clinical efficacy, symptoms and signs and recurrence rate were compared between the two groups.Results ①There′s no significant difference of total effective rate between the observed group(93.55%) and the control group(88.71%)(P>0.05).②After treatment, the increased secretion, vaginal itching, vaginal burning, vaginal wall congestion and secretions microscope cleanliness were significantly improved than that before the treatment in both of the groups(P<0.01).③The recurrence rate in the observed group(24.24%) was significantly lower than the control group (60%).Conclusion Vitamin B could improve the symptoms and reduce relapse rate of senile vaginitis .