CAJ | 학술논문

类固醇激素是高效能的生物化学物质，在多种生理活动中发挥显著的调节作用，但在体内的含量极低，因此对其进行准确定量具有重要意义。在各种检测方法中，色谱-质谱联用技术因具有高效、快速、灵敏的优点而得以广泛应用。笔者综述近年来色谱-质谱联用技术在内源性类固醇激素测定中的应用，为进一步的临床研究提供参考依据。
류고순격소시고효능적생물화학물질，재다충생리활동중발휘현저적조절작용，단재체내적함량겁저，인차대기진행준학정량구유중요의의。재각충검측방법중，색보-질보련용기술인구유고효、쾌속、령민적우점이득이엄범응용。필자종술근년래색보-질보련용기술재내원성류고순격소측정중적응용，위진일보적림상연구제공삼고의거。
Steroid hormones were chemical compounds of high efficiency , which played a significant role in various physiologi-cal activities.However, the concentrations of hormones in vivo were extremely low, so it was very important for their accurate quantifi-cation.Chromatography-mass spectrometry technology was widely employed because of advances in high efficient , rapid and sensitive. The application of steroid hormone analysis by chromatography-mass spectrometry was reviewed in this paper , which could provide ref-erence for furthuer clinical research .