CAJ | 학술논문

对杀虫剂三氟甲吡醚的合成工艺进行改进，提高了总收率。先对对苯二酚的1个羟基进行保护，再经缩合、水解、氯化、醚化，得到3-[2,6-二氯-4-(3,3-二氯烯丙氧基)苯氧基]丙-1-醇，最后与2-氯-5-三氟甲基吡啶反应得到目标产物三氟甲吡醚。该工艺简单经济，条件温和，适合工业化生产。
대살충제삼불갑필미적합성공예진행개진，제고료총수솔。선대대분이분적1개간기진행보호，재경축합、수해、록화、미화，득도3-[2,6-이록-4-(3,3-이록희병양기)분양기]병-1-순，최후여2-록-5-삼불갑기필정반응득도목표산물삼불갑필미。해공예간단경제，조건온화，괄합공업화생산。
The synthetic process of pyridalyl was improved and the yield was raised. One hydroxyl of hydroquinone was protected first, then the intermediate of 3-[2,6-dichloro-4-(3,3-dichloroallyloxy)phenoxy]propyl-1-alcohol was synthetized through condensation, hydrolysis, chlorination, etherification. At last the intermediate reacted with 2-chloro-5-trifluoromethyl pyridine. The process had advantages as simple operations,mild reaction conditions. It was valuable to be used in industrial scale.