CAJ | 학술논문

采用静态染毒法，研究了双酚 A（bisphenol A，BPA）对河蚬（Corbicula fluminea）的急性毒性以及在96h - LC50的1/10、1/8、1/4、1/2亚急性质量浓度胁迫下耗氧率和排氨率，以及抗氧化酶系统中超氧化物歧化酶（ SOD）、过氧化氢酶（CAT）活性的变化，探究河蚬在 BPA 胁迫下的生物学响应.结果显示：BPA 对河蚬96 h-LC50为6.34 mg/ L；亚急性毒性指标耗氧率、排氨率以及 SOD、CAT 对 BPA 比较敏感，在试验质量浓度范围内（0.63~3.17 mg/ L）河蚬耗氧率、排氨率以及2种酶活性变化均呈现先下降后上升再下降的趋势，有较好的一致性和规律性. BPA 对河蚬产生了氧化损伤，具有一定的毒性作用.
채용정태염독법，연구료쌍분 A（bisphenol A，BPA）대하현（Corbicula fluminea）적급성독성이급재96h - LC50적1/10、1/8、1/4、1/2아급성질량농도협박하모양솔화배안솔，이급항양화매계통중초양화물기화매（ SOD）、과양화경매（CAT）활성적변화，탐구하현재 BPA 협박하적생물학향응.결과현시：BPA 대하현96 h-LC50위6.34 mg/ L；아급성독성지표모양솔、배안솔이급 SOD、CAT 대 BPA 비교민감，재시험질량농도범위내（0.63~3.17 mg/ L）하현모양솔、배안솔이급2충매활성변화균정현선하강후상승재하강적추세，유교호적일치성화규률성. BPA 대하현산생료양화손상，구유일정적독성작용.
The acute toxicities of bisphenol A(BPA)to the Asian clams(Corbicula fluminea)and the toxic effects of BPA on the oxygen consumption rate(OCR),the ammonia excretory rate(AER),and the activity of antioxi-dant enzymes including superoxide dismutase( SOD)and catalase( CAT)in the clams at the concentrations of 1 / 2,1 / 4,1 / 8,1 / 10 of 96h - LC50 were investigated. The results showed that the 96 h-LC50 of BPA to the clams was 6. 34 mg / L. The sensitive response of OCR,AER,SOD and CAT of the clams to BPA exposure in the range of 0. 63 ~ 3. 17 mg / L showed a typical pattern. This may indicate that BPA had oxidative stress and toxic effects on the growth of Asian clams.