中国医药
中國醫藥
중국의약
CHINA MEDICINE
2014年
1期
109-111
,共3页
陈祥楠%胡祖荣%杨世辉%黄伟坚%黎昆伟%贾杰
陳祥楠%鬍祖榮%楊世輝%黃偉堅%黎昆偉%賈傑
진상남%호조영%양세휘%황위견%려곤위%가걸
分娩%镇痛%地佐辛%舒芬太尼%瘙痒
分娩%鎮痛%地佐辛%舒芬太尼%瘙癢
분면%진통%지좌신%서분태니%소양
Labor%Analgesia%Dezocine%Sulfentanyl%Pruritus
目的 探讨地佐辛对鞘内舒芬太尼分娩镇痛所致瘙痒的治疗作用.方法 选取90例美国麻醉师协会分级Ⅰ～Ⅱ级、单胎、足月(≥37周)、枕前位妊娠拟经阴道分娩,行鞘内注射舒芬太尼5μg分娩镇痛后24 h内瘙痒的产妇,完全随机分成2组(每组45例).地佐辛组静脉注射地佐辛5 mg(1 ml),0.9％氯化钠注射液组静脉注射0.9％氯化钠注射液1 ml.瘙痒评分、镇痛评分、镇静评分每5分钟记录1次,记录30 min.结果 地佐辛组瘙痒的治疗有效率明显高于0.9％氯化钠注射液组[80.0％(36/45)比15.6％ (7/45),P＜0.01],2组的镇痛评分比较差异无统计学意义[(2.2±0.5)分比(2.0±0.3)分](p＞0.05),2组的镇静评分比较差异有统计学意义(P＜0.05).结论 地佐辛5 mg静脉注射可以有效地治疗鞘内舒芬太尼分娩镇痛所引起的瘙痒.
目的 探討地佐辛對鞘內舒芬太尼分娩鎮痛所緻瘙癢的治療作用.方法 選取90例美國痳醉師協會分級Ⅰ～Ⅱ級、單胎、足月(≥37週)、枕前位妊娠擬經陰道分娩,行鞘內註射舒芬太尼5μg分娩鎮痛後24 h內瘙癢的產婦,完全隨機分成2組(每組45例).地佐辛組靜脈註射地佐辛5 mg(1 ml),0.9％氯化鈉註射液組靜脈註射0.9％氯化鈉註射液1 ml.瘙癢評分、鎮痛評分、鎮靜評分每5分鐘記錄1次,記錄30 min.結果 地佐辛組瘙癢的治療有效率明顯高于0.9％氯化鈉註射液組[80.0％(36/45)比15.6％ (7/45),P＜0.01],2組的鎮痛評分比較差異無統計學意義[(2.2±0.5)分比(2.0±0.3)分](p＞0.05),2組的鎮靜評分比較差異有統計學意義(P＜0.05).結論 地佐辛5 mg靜脈註射可以有效地治療鞘內舒芬太尼分娩鎮痛所引起的瘙癢.
목적 탐토지좌신대초내서분태니분면진통소치소양적치료작용.방법 선취90례미국마취사협회분급Ⅰ～Ⅱ급、단태、족월(≥37주)、침전위임신의경음도분면,행초내주사서분태니5μg분면진통후24 h내소양적산부,완전수궤분성2조(매조45례).지좌신조정맥주사지좌신5 mg(1 ml),0.9％록화납주사액조정맥주사0.9％록화납주사액1 ml.소양평분、진통평분、진정평분매5분종기록1차,기록30 min.결과 지좌신조소양적치료유효솔명현고우0.9％록화납주사액조[80.0％(36/45)비15.6％ (7/45),P＜0.01],2조적진통평분비교차이무통계학의의[(2.2±0.5)분비(2.0±0.3)분](p＞0.05),2조적진정평분비교차이유통계학의의(P＜0.05).결론 지좌신5 mg정맥주사가이유효지치료초내서분태니분면진통소인기적소양.
Objective To investigate the effect of dezocine on the spinal sulfentanyl-induced pruritus during labor analgesia.Methods Ninety patients with american society of anesthesiologists physical status 1-2,nulliparous and undergoing a spontaneous labor (≥37 weeks of gestation) with a live,singleton fetus,receiving spinal sulfentanyl-induced prutitus during labor analgesia (in postoperative 24 h) were randomly allocated to receive 5 mg dezocine (1 ml) (dezocine group,45 cases) or 1 ml 0.9％ sodium chloride injection (0.9％ sodium chloride injection group,45 cases)intravenously.Pruritus,sedative and the level of postoperative pain were assessed every 5 min till the end of the study period (30 min).Results The treatment success rate in the dezocine group was higher than that in the 0.9％ sodium chloride injection group [80.0％ (36/45) vs 15.6％ (7/45),P ＜0.01].Other side effects,such as decreased analgesia,were not significantly different between groups.Sedation scores between the two groups was statistically significant [(2.2 ± 0.5) scores vs (2.0 ± 0.3) scores].Conclusion Dezocine is an efficient drug treatment for spinal sulfentanyl-induced pruritus during labor analgesia.
