CAJ | 학술논문

目的：探讨晚期糖基化终末产物对下肢深静脉血栓后遗症的影响。方法将44例 PTS 患者设为 PTS组、30例 DVT 非 PTS 患者设为非 PTS 组及30例正常患者设为对照组，分别测定 AGEs（Advanced Glycation end products）进行比较，同时按照栓塞严重程度及血流动力学分级分别进行统计学比较。结果PTS 组、非 PTS 组、对照组晚期糖基化终末产物含量对比差异有统计学意义（P＜0．05），PTS 患者下肢栓塞程度与血清 AGEs 含量成正相关， PTS 患者患肢血流动力学分级与血清 AGEs 含量呈正相关。结论AGEs 与下肢 DVT 及 PTS 的形成与预后密切相关。
목적：탐토만기당기화종말산물대하지심정맥혈전후유증적영향。방법장44례 PTS 환자설위 PTS조、30례 DVT 비 PTS 환자설위비 PTS 조급30례정상환자설위대조조，분별측정 AGEs（Advanced Glycation end products）진행비교，동시안조전새엄중정도급혈류동역학분급분별진행통계학비교。결과PTS 조、비 PTS 조、대조조만기당기화종말산물함량대비차이유통계학의의（P＜0．05），PTS 환자하지전새정도여혈청 AGEs 함량성정상관， PTS 환자환지혈류동역학분급여혈청 AGEs 함량정정상관。결론AGEs 여하지 DVT 급 PTS 적형성여예후밀절상관。
Objective To explore the effects of advanced glycation end products on the postthrombosis syndrome. Methods The 44 patients with PTS as PTS group,30 cases of DVT patients without PTS as non-PTS group and 30 normal person as control group,AGEs were measured by comparing,the same time according to the severity of embolic and hemodynamic classification for statistical comparison.Results PTS group,non-PTS group,the control group of advanced glycation end products content and contrast the differences were statistically significant (P <0.05),PTS em-bolism in patients with lower limb AGEs content and serum level of positive correlation hemodynamics in patients with limb grading PTS was positively correlated with serum AGEs content.Conclusion The formation and prognosis of lower extremity DVT and PTS is closely related to AGEs.