CAJ | 학술논문

目的：探讨恶性血液病合并IFI患者易感染因素的临床特点。方法对我院2001年1月---2012年1月间的80例恶性血液病合并IFI患者的临床资料、致病菌种类、易感因素等进行回顾性分析，其临床治疗主要分三组，比较其临床疗效及不良反应发生的例数。结果恶性血液病合并 IFI的易感染因素主要有与使用抗菌素的关系、粒细胞缺乏、与病期和化疗强度的关系等。结论 IFI已成为恶性血液病粒细胞缺乏期的重要合并症及死亡原因，加强对血液病合并真菌感染的认识及提高诊治水平非常重要。
목적：탐토악성혈액병합병IFI환자역감염인소적림상특점。방법대아원2001년1월---2012년1월간적80례악성혈액병합병IFI환자적림상자료、치병균충류、역감인소등진행회고성분석，기림상치료주요분삼조，비교기림상료효급불량반응발생적례수。결과악성혈액병합병 IFI적역감염인소주요유여사용항균소적관계、립세포결핍、여병기화화료강도적관계등。결론 IFI이성위악성혈액병립세포결핍기적중요합병증급사망원인，가강대혈액병합병진균감염적인식급제고진치수평비상중요。
Objective On patients with malignant blood disease merging IFI the clinical characteristics of susceptible factors .Methods In our hospital in January 2001 -January 2012 between the clinical data of 80 patients with malignant blood disease merging IFI,pathogenic bacteria species and susceptible factors were retrospec-tively analyzed,and its clinical treatment mainly is divided into three groups ,to compare the clinical curative effect and the number of cases of adverse reactions occurs. Result Malignant blood disease merging IFI susceptible factors mainly has the relationship with the use of antibiotics ,lack of granulocyte,relationship with the illness and the intensity of chemotherapy,etc.Conclusion IFI have become important complication of granulocyte phase lack of hematologic malignancies and the cause of death ,to strengthen the understanding of haematology merge fungus infection and improve the level of diagnosis and treatment are very important .