世界中西医结合杂志
世界中西醫結閤雜誌
세계중서의결합잡지
WORLD JOURNAL OF TRADITIONAL CHINESE AND WESTERN MEDICINE
2014年
5期
517-518,521
,共3页
高血压%肝阳上亢%天麻钩藤饮加减方%硝苯地平缓释片
高血壓%肝暘上亢%天痳鉤籐飲加減方%硝苯地平緩釋片
고혈압%간양상항%천마구등음가감방%초분지평완석편
Hypertension%Hyperactivity of Liver Yang%Modified Tianma Gouteng Decoction%Sus-tained Released Nifedipine Tablets
目的：观察天麻钩藤饮加减方联合硝苯地平缓释片治疗高血压的临床疗效。方法75例高血压患者经中医辨证均为肝阳上亢型，随机分为治疗组38例和对照组37例。两组均给予硝苯地平缓释片，每次20 mg，2次·d-1。治疗组同时给予天麻钩藤饮加减方，水煎服，1剂·d-1。两组均治疗8周，8周后观察疗效。结果治疗组总有效率为94.7%（36/38），明显高于对照组总有效率83.8%（31/37）（P﹤0.05）；治疗后治疗组收缩压和舒张压分别为（129.8±4.3）mm Hg和（84.9±4.7）mm Hg，较治疗前明显降低（ P﹤0.05）；治疗后对照组收缩压和舒张压与治疗前比较虽下降但差异无统计学意义（P﹥0.05）。结论天麻钩藤饮加减方联合硝苯地平缓释片治疗肝阳上亢型高血压，降压效果明显，能显著改善高血压引起的相关症状，安全性高，适合临床推广。
目的：觀察天痳鉤籐飲加減方聯閤硝苯地平緩釋片治療高血壓的臨床療效。方法75例高血壓患者經中醫辨證均為肝暘上亢型，隨機分為治療組38例和對照組37例。兩組均給予硝苯地平緩釋片，每次20 mg，2次·d-1。治療組同時給予天痳鉤籐飲加減方，水煎服，1劑·d-1。兩組均治療8週，8週後觀察療效。結果治療組總有效率為94.7%（36/38），明顯高于對照組總有效率83.8%（31/37）（P﹤0.05）；治療後治療組收縮壓和舒張壓分彆為（129.8±4.3）mm Hg和（84.9±4.7）mm Hg，較治療前明顯降低（ P﹤0.05）；治療後對照組收縮壓和舒張壓與治療前比較雖下降但差異無統計學意義（P﹥0.05）。結論天痳鉤籐飲加減方聯閤硝苯地平緩釋片治療肝暘上亢型高血壓，降壓效果明顯，能顯著改善高血壓引起的相關癥狀，安全性高，適閤臨床推廣。
목적：관찰천마구등음가감방연합초분지평완석편치료고혈압적림상료효。방법75례고혈압환자경중의변증균위간양상항형，수궤분위치료조38례화대조조37례。량조균급여초분지평완석편，매차20 mg，2차·d-1。치료조동시급여천마구등음가감방，수전복，1제·d-1。량조균치료8주，8주후관찰료효。결과치료조총유효솔위94.7%（36/38），명현고우대조조총유효솔83.8%（31/37）（P﹤0.05）；치료후치료조수축압화서장압분별위（129.8±4.3）mm Hg화（84.9±4.7）mm Hg，교치료전명현강저（ P﹤0.05）；치료후대조조수축압화서장압여치료전비교수하강단차이무통계학의의（P﹥0.05）。결론천마구등음가감방연합초분지평완석편치료간양상항형고혈압，강압효과명현，능현저개선고혈압인기적상관증상，안전성고，괄합림상추엄。
Objective To observe the clinical efficacy on hypertension treated with modified Tianma Gouteng Decoction and Sustained Released Nifedipine Tablets. Methods Seventy-five cases of hyperten-sion were differentiated as hyperactivity of liver yang in traditional Chinese medicine and were randomized in-to a treatment group(38 cases)and a control group(37 cases). The Sustained Released Nifedipine Tablets were prescribed in the two groups,20mg each time,twice a day. In the treatment,the modified Tianma Gout-eng Decoction was prescribed for oral administration,one dose a day. The treatment lasted for 8 weeks in the two groups. The efficacy was observed in 8 weeks. Results The total effective rate was 94. 7%(36/38), which was higher apparently than 83. 8%(31/37)in the control group. After treatment,the systolic pressure and diastolic pressure were(129. 8 ± 4. 3)mm Hg and(84. 9 ± 4. 7)mm Hg,which were lower apparently than those before treatment(P﹤0. 05). After treatment,the systolic pressure and diastolic pressure were re-duced,but the differences were not significant as compared those before treatment in the control group( P﹥0. 05). Conclusion The combined medication of the modified Tianma Gouteng Decoction and Sustained Re-leased Nifedipine Tablets achieves the remarkable effects on hypertension differentiated as hyperactivity of liver yang. It relieves significantly the relevant symptoms induced by hypertension and is good at safety. Hence,this therapy is suitable to be promoted in clinical practice.
