CAJ | 학술논문

目的：观察电针联合硫辛酸治疗2型糖尿病周围神经病变的临床疗效，并探讨其治疗机制。方法将符合病例纳入标准的120例患者随机分为电针组、药物组和联合组，各40例。电针组采用电针治疗，药物组仅采用硫辛酸注射治疗，联合组采用电针联合硫辛酸治疗。三组患者在治疗2个疗程后分别进行NCV速度测定、MNSI评分及疗效评定，比较三组临床疗效。结果三组病例经相应方法治疗2个疗程后，NCV传导速度均增快，其中联合组神经传导速度增快最明显；联合组的MNSI评分降幅高于药物组和电针组；电针组痊愈率为27.5%，总有效率为72.5%；药物组痊愈率为37.5%，总有效率为77.5%；联合组痊愈率为72.5%，总有效率为95.0%；联合组痊愈率及总有效率均明显优于电针组和药物组，三组比较差异有统计学意义（ P﹤0.05）。结论电针配合硫辛酸治疗2型糖尿病周围神经病变疗效显著。
목적：관찰전침연합류신산치료2형당뇨병주위신경병변적림상료효，병탐토기치료궤제。방법장부합병례납입표준적120례환자수궤분위전침조、약물조화연합조，각40례。전침조채용전침치료，약물조부채용류신산주사치료，연합조채용전침연합류신산치료。삼조환자재치료2개료정후분별진행NCV속도측정、MNSI평분급료효평정，비교삼조림상료효。결과삼조병례경상응방법치료2개료정후，NCV전도속도균증쾌，기중연합조신경전도속도증쾌최명현；연합조적MNSI평분강폭고우약물조화전침조；전침조전유솔위27.5%，총유효솔위72.5%；약물조전유솔위37.5%，총유효솔위77.5%；연합조전유솔위72.5%，총유효솔위95.0%；연합조전유솔급총유효솔균명현우우전침조화약물조，삼조비교차이유통계학의의（ P﹤0.05）。결론전침배합류신산치료2형당뇨병주위신경병변료효현저。
Objective To observe the clinical efficacy on type 2 diabetes peripheral neuropathy ( type 2 DPN)treated with electroacupuncture( EA)and lipoic acid so as to explore the mechanism on treat-ment. Methods One hundred and twenty cases that met the inclusive standards were randomized into EA group,medicine group and the joint-therapy group,40 cases in each one. In EA,EA therapy was used. In the medicine group,lipoic acid injection was used. In the joint-therapy group,EA and lipoic acid were ap-plied in combination. After 2 sessions of treatment,NCV detection,MNSI scoring and efficacy evaluation were performed in the three groups. The clinical efficacy was compared among the three groups. Results After treatment for 2 sessions,NCV was increased,in which the increase in the joint-therapy group was the most obvious. The decrease amplitude of MNSI score in the joint-therapy group was higher than that in the medi-cine group and EA group. In EA group,the curative rate was 27. 5% and the total effective rate was 72. 5%. In the medicine group,the curative rate was 37. 5% and the total effective rate was 77. 5%. In the joint-therapy group,the curative rate was 72. 5% and the total effective rate was 95. 0%. The curative rate and to-tal effective rate in the joint-therapy group were superior apparently to EA group and the medicine group,in-dicating the significant difference(P﹤0. 05). Conclusion EA combined with lipoic acid achieves the sig-nificant efficacy on type 2 DPN.