CAJ | 학술논문

目的：探索初治继发性肺结核中医证候规律。方法在全国不同地域14家单位对1500例初治继发性肺结核患者进行中医四诊信息采集表的问卷调查，应用中医四诊信息采集软件，系统规范化录入肺结核中医四诊信息及各项辅助检查。建立数据库，进行统计分析。结果本研究人群证候主要集中在肺阴虚证（40.3%）、阴虚火旺证（20.4%）、气阴两虚证（19.5%）；肺阴虚证的相关因素为白介素-1，阴虚火旺证的相关因素为白介素-10，气阴两虚证的相关因素为肿瘤坏死因子，阴阳两虚证的相关因素为CD4=淋巴细胞、干扰素-γ，肺脾两虚证的相关因素为肿瘤坏死因子，肺肾阴虚证无相关因素。总结出临床上常见6个证候的症状、舌、脉。结论对肺结核客观指标的研究非常必要，本课题初步总结出11个证候相关的免疫因子。初步总结出初治继发性肺结核中医证候规律。
목적：탐색초치계발성폐결핵중의증후규률。방법재전국불동지역14가단위대1500례초치계발성폐결핵환자진행중의사진신식채집표적문권조사，응용중의사진신식채집연건，계통규범화록입폐결핵중의사진신식급각항보조검사。건립수거고，진행통계분석。결과본연구인군증후주요집중재폐음허증（40.3%）、음허화왕증（20.4%）、기음량허증（19.5%）；폐음허증적상관인소위백개소-1，음허화왕증적상관인소위백개소-10，기음량허증적상관인소위종류배사인자，음양량허증적상관인소위CD4=림파세포、간우소-γ，폐비량허증적상관인소위종류배사인자，폐신음허증무상관인소。총결출림상상상견6개증후적증상、설、맥。결론대폐결핵객관지표적연구비상필요，본과제초보총결출11개증후상관적면역인자。초보총결출초치계발성폐결핵중의증후규률。
Objective To explore the rules of Chinese medicine( TCM)syndromes in secondary pul-monary tuberculosis( TB)after the initial treatment. Methods In 14 organizations of different regions in Chi-na,1500 cases of initially treated secondary TB received the questionnaire on four diagnostic information col-lection of TCM. The software of four diagnostic information collection of TCM was adopted for the systematic and normative record of the four diagnostic information and every accessory examinations. The database was set up for statistical analysis. Results In this study,the syndromes were mainly differentiated as lung yin de-ficiency(40. 3%),excessive fire due to yin deficiency(20. 4%)and deficiency of qi and yin(19. 5%). The correlative factor of lung yin deficiency syndrome was IL-1,that of excessive fire due to yin deficiency was IL-10 and that of deficiency of qi and yin was TNF,that of yin and yang deficiency was CD4= lymphocyte and interferon-γ,that of lung and spleen deficiency was TNF and there was no correlative factor to yin defi-ciency of lung and kidney. The symptoms,tongue and pulse conditions were summarized in six common syn-dromes in clinic. Conclusion It is very necessary to study the objective indexes of TB. This study summari-zes initially 11 correlative immune factors to the syndromes.