中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
16期
2411-2413
,共3页
肺炎支原体抗体%过敏性紫癜%检测价值%免疫功能
肺炎支原體抗體%過敏性紫癜%檢測價值%免疫功能
폐염지원체항체%과민성자전%검측개치%면역공능
Mycoplasma pneumoniae antibody%Allergic purpura%Detection value%Immune function
目的 探讨肺炎支原体抗体IgM(MP-IgM)阳性在过敏性紫癜(HSP)患儿中的检测价值.方法 选取80例HSP患儿为研究对象(观察组),另选取40例健康儿为对照组,比较两组MP-IgM的阳性率,并分析HSP合并MP-IgM阳性患儿免疫功能的变化.结果 观察组MP-IgM阳性的患儿有32例,阳性率为40.0％.观察组的MP-IgM的阳性率显著高于对照组(P＜0.05).观察组中的CD4+的百分率显著低于对照组,CD8+ 的百分率显著高于对照组,CD4+ /CD8+ 比值显著低于对照组,NK显著低于对照组(P＜0.05).MP-IgM阳性组的CD8+ 的百分率显著高于阴性组,CD4+/CD8+比值显著低于阴性组,NK的百分率显著低于阴性组(P＜0.05).结论 MP感染是HSP患儿的重要病因,其可加重患儿的免疫功能紊乱,在HSP的发生和发展中有重要作用.
目的 探討肺炎支原體抗體IgM(MP-IgM)暘性在過敏性紫癜(HSP)患兒中的檢測價值.方法 選取80例HSP患兒為研究對象(觀察組),另選取40例健康兒為對照組,比較兩組MP-IgM的暘性率,併分析HSP閤併MP-IgM暘性患兒免疫功能的變化.結果 觀察組MP-IgM暘性的患兒有32例,暘性率為40.0％.觀察組的MP-IgM的暘性率顯著高于對照組(P＜0.05).觀察組中的CD4+的百分率顯著低于對照組,CD8+ 的百分率顯著高于對照組,CD4+ /CD8+ 比值顯著低于對照組,NK顯著低于對照組(P＜0.05).MP-IgM暘性組的CD8+ 的百分率顯著高于陰性組,CD4+/CD8+比值顯著低于陰性組,NK的百分率顯著低于陰性組(P＜0.05).結論 MP感染是HSP患兒的重要病因,其可加重患兒的免疫功能紊亂,在HSP的髮生和髮展中有重要作用.
목적 탐토폐염지원체항체IgM(MP-IgM)양성재과민성자전(HSP)환인중적검측개치.방법 선취80례HSP환인위연구대상(관찰조),령선취40례건강인위대조조,비교량조MP-IgM적양성솔,병분석HSP합병MP-IgM양성환인면역공능적변화.결과 관찰조MP-IgM양성적환인유32례,양성솔위40.0％.관찰조적MP-IgM적양성솔현저고우대조조(P＜0.05).관찰조중적CD4+적백분솔현저저우대조조,CD8+ 적백분솔현저고우대조조,CD4+ /CD8+ 비치현저저우대조조,NK현저저우대조조(P＜0.05).MP-IgM양성조적CD8+ 적백분솔현저고우음성조,CD4+/CD8+비치현저저우음성조,NK적백분솔현저저우음성조(P＜0.05).결론 MP감염시HSP환인적중요병인,기가가중환인적면역공능문란,재HSP적발생화발전중유중요작용.
Objective To investigate the detection value of the positive rate of MP-IgM in children with Henoch-Schonlein purpura (HSP).Methods 80 HSP patients were chosen as the research subjects (the observation group),the other 40 healthy children were chosen as research subjects(the control group).The positive rate of MP-IgM,and positive changes in immune function of children with HSP combined with MP-IgM were analyzed in two groups.Results 32 cases were MP-IgM positive in the observation group,the positive rate was 40％.The MP-IgM positive rate in the observation group was significantly higher than that in the control group(P ＜0.05).The percentage of CD4+ in the observation group was significantly lower than that in the control group,the percentage of CD8+ was significantly higher than that in the control group,CD4+/CD8+ was significantly lower than that in the control group,NK was significantly lower than that in the control group(P ＜0.05).The percentage of CD8+ in MP-IgM positive group was significantly higher than that in the negative group,the percentage of CD4+/CD8+ was significantly lower than that in the negative group,the percentage of NK was significantly lower than that in the negative group (P ＜ 0.05).Conclusion MP infection is an important cause of HSP,it can aggravate the immune dysfunction and play an important role in the occurrence and development of HSP.
