CAJ | 학술논문

　　目的比较四种不同清肠方法的清肠效果、肠道内气泡产生情况、不良反应发生情况及患者下一次服用意愿，探索快捷、有效、安全的清肠方法。方法选取240例准备做结肠镜检查的患者，随机分为四组：A组服用20％甘露醇溶液，B组服用聚乙二醇4000散剂，C组服用聚乙二醇4000散剂联合枸橼酸莫沙必利分散片，D组服用磷酸钠盐口服液。比较四组患者肠道清洁程度、肠道内气泡产生情况和不良反应发生情况。结果 C组和D组的清肠效果优于A组和B组，D组的不良反应发生率明显低于其余各组（ P＜0.05），四组的肠道内气泡产生率差异无统计学意义（ P＞0.05）。结论聚乙二醇联合莫沙必利及磷酸钠盐这两种清肠方法较理想，磷酸钠盐清肠不良反应发生率最低。
　　목적비교사충불동청장방법적청장효과、장도내기포산생정황、불량반응발생정황급환자하일차복용의원，탐색쾌첩、유효、안전적청장방법。방법선취240례준비주결장경검사적환자，수궤분위사조：A조복용20％감로순용액，B조복용취을이순4000산제，C조복용취을이순4000산제연합구연산막사필리분산편，D조복용린산납염구복액。비교사조환자장도청길정도、장도내기포산생정황화불량반응발생정황。결과 C조화D조적청장효과우우A조화B조，D조적불량반응발생솔명현저우기여각조（ P＜0.05），사조적장도내기포산생솔차이무통계학의의（ P＞0.05）。결론취을이순연합막사필리급린산납염저량충청장방법교이상，린산납염청장불량반응발생솔최저。
Objective To compare the effects of intestinal preparation , reverse drug reactions , bubbles and tolerability among 4 different intestinal preparation methods , in order to seek out simple fast and safe intestinal prepa-ration methods .Methods Two hundred and forty patients undergoing colonoscopy were randomly divided into 4 groups with 60 cases in each group .Group A received mannital , group B received Macrogol 4000 powder for oral so-lution, group C received Macrogol 4000 powder for oral solution combined with Mosapride citrate dispersible tablets , group D received oral sodium phosphate .Effects of bowel cleansing , reverse drug reactions and bubbles were ob-served and compared .Results The intestinal cleanliness of group C and group D were superior to group A and group B .Among the four groups , group D has the lest rate of reverse drug reactions ( P<0.05 ) .Four groups showed the similar rate of bubbles .Conclusion Both methods , no matter the combined use of Macrogol 4000 powder for oral so-lution and Mosapride citrate dispersible tablets ,or oral sodium phosphate have better quality of bowel cleansing , and oral sodium phosphate has the lest rate of reverse drug reactions .