中国保健营养（中旬刊）
中國保健營養（中旬刊）
중국보건영양（중순간）
China Hwalth Care & nutrition
2013年
11期
52-52
,共1页
急性脑梗塞%代谢综合征%瘦素%肿瘤坏死因子%颈动脉斑块
急性腦梗塞%代謝綜閤徵%瘦素%腫瘤壞死因子%頸動脈斑塊
급성뇌경새%대사종합정%수소%종류배사인자%경동맥반괴
Acute erebral infarction%metabolic syndrome%leptin%TNF%carotid plaque
目的：探讨急性脑梗塞（ACI）并代谢综合征（MS）患者颈动脉斑块性质以及与血清瘦素、TNF的关系。方法：将126例通过彩色多普勒筛查出有颈动脉粥样硬化斑块的ACI患者分为MS组及非MS组，比较两组血清瘦素、TNF水平，借助1.5T核磁共振血管成像(CE-MRA)对颈动脉进展期斑块进行统计，并做比较。运用多元逐步logistic回归分析ACI并MS患者血清瘦素、TNF水平及与颈动脉进展性斑块的关系。结果：ACI并MS组血清瘦素、TNF水平明显高于非MS组（P<0.05）,MS组颈动脉进展性斑块发生率高于非MS组（P<0.05），ACI并MS患者血清瘦素、TNF水平与颈动脉进展性斑块具有相关性（OR=0．073, P<0.05）。结论：MS是脑血管病重要危险因素，血清瘦素、TNF可能是颈动脉斑块进展的原因之一。
目的：探討急性腦梗塞（ACI）併代謝綜閤徵（MS）患者頸動脈斑塊性質以及與血清瘦素、TNF的關繫。方法：將126例通過綵色多普勒篩查齣有頸動脈粥樣硬化斑塊的ACI患者分為MS組及非MS組，比較兩組血清瘦素、TNF水平，藉助1.5T覈磁共振血管成像(CE-MRA)對頸動脈進展期斑塊進行統計，併做比較。運用多元逐步logistic迴歸分析ACI併MS患者血清瘦素、TNF水平及與頸動脈進展性斑塊的關繫。結果：ACI併MS組血清瘦素、TNF水平明顯高于非MS組（P<0.05）,MS組頸動脈進展性斑塊髮生率高于非MS組（P<0.05），ACI併MS患者血清瘦素、TNF水平與頸動脈進展性斑塊具有相關性（OR=0．073, P<0.05）。結論：MS是腦血管病重要危險因素，血清瘦素、TNF可能是頸動脈斑塊進展的原因之一。
목적：탐토급성뇌경새（ACI）병대사종합정（MS）환자경동맥반괴성질이급여혈청수소、TNF적관계。방법：장126례통과채색다보륵사사출유경동맥죽양경화반괴적ACI환자분위MS조급비MS조，비교량조혈청수소、TNF수평，차조1.5T핵자공진혈관성상(CE-MRA)대경동맥진전기반괴진행통계，병주비교。운용다원축보logistic회귀분석ACI병MS환자혈청수소、TNF수평급여경동맥진전성반괴적관계。결과：ACI병MS조혈청수소、TNF수평명현고우비MS조（P<0.05）,MS조경동맥진전성반괴발생솔고우비MS조（P<0.05），ACI병MS환자혈청수소、TNF수평여경동맥진전성반괴구유상관성（OR=0．073, P<0.05）。결론：MS시뇌혈관병중요위험인소，혈청수소、TNF가능시경동맥반괴진전적원인지일。
Objective:To explore the relationship of serum leptin and TNF with carotid plaque’s character in Acute erebral infarction (ACI)complicated by metabolic syndrome(MS).Method:126 ACI patients with carotis plaque were selected by transcranial Doppler were divided into MS group and non-MS group.The levels of serum leptin and TNF were compared in two groups. Carotis developed plaque in two groups were statistic and compared. The relationship of serum leptin and TNF with carotid plaque’s character in ACI complicated by MS were examined by Multiple logistic regression analysis·Result:The levels of serum leptin and TNF of ACI with MS were higher than those of ACI with non-MS.The incident of Carotis developed plaque in ACI with MS were higher than in ACI with non-MS.There was positive correlation beteen the levels of serum leptin and TNF with the incident of carotis developed plaque in ACI with MS(OR=0.073, P<0.05). Conclusion:MS is important risk factor of erebral infarction. The levels of serum leptin and TNF may be one of factors of Carotis developed plaque.
