CAJ | 학술논문

目的：探讨肝脏特异性对比剂Gd-EOB-DTPA对Gd-DTPA延迟期呈等或高信号小肝癌的诊断价值。方法：回顾性分析33例肝硬化小肝癌患者（41例病灶）在Gd-DTPA 及Gd-EOB-DTPA 常规平扫及动态增强各期的表现，重点观察病灶在Gd-EOB-DTPA肝胆期的表现。结果：41个小肝癌病灶中7个于Gd-DTPA 延迟期呈等或高信号，其中6个在Gd-EOB-DTPA增强扫描肝胆期表现为低信号，1个表现为稍高信号；其余34个小肝癌病灶在Gd-DTPA 和Gd-EOB-DTPA增强扫描中均表现为“速升速降”型强化方式。结论：Gd-EOB-DTPA 动态增强联合肝胆期扫描能够为在 Gd-DT-PA延迟期呈等或高信号小肝癌的定性诊断提供更多信息，提高不典型小肝癌的检出率。
목적：탐토간장특이성대비제Gd-EOB-DTPA대Gd-DTPA연지기정등혹고신호소간암적진단개치。방법：회고성분석33례간경화소간암환자（41례병조）재Gd-DTPA 급Gd-EOB-DTPA 상규평소급동태증강각기적표현，중점관찰병조재Gd-EOB-DTPA간담기적표현。결과：41개소간암병조중7개우Gd-DTPA 연지기정등혹고신호，기중6개재Gd-EOB-DTPA증강소묘간담기표현위저신호，1개표현위초고신호；기여34개소간암병조재Gd-DTPA 화Gd-EOB-DTPA증강소묘중균표현위“속승속강”형강화방식。결론：Gd-EOB-DTPA 동태증강연합간담기소묘능구위재 Gd-DT-PA연지기정등혹고신호소간암적정성진단제공경다신식，제고불전형소간암적검출솔。
Objective:To investigate the value of Gd-EOB-DTPA hepatobiliary phase for diagnosis of small hepatocel-lular carcinoma (SHCC)with iso/hyper-intensity in delayed phase of Gd-DTPA.Methods:A total of 33 cirrhotic patients with 41 confirmed SHCC were analyzed retrospectively.The manifestations of lesions on conventional native phase and dy-namic contrast enhancement of both Gd-DTPA and Gd-EOB-DTPA were observed,especially on hepatobiliary phase of Gd-EOB-DTPA.Results:Of the 41 SHCC,7 lesions showed iso/hyper-intensity in delayed phase of Gd-DTPA,including 6 le-sions showing hypo-intensity in hepatobiliary phase of Gd-EOB-DTPA and one showing slight hyper-intensity.The rest 34 lesions showed"rapid enhancing and rapid washout"in dynamic contrast enhancement with Gd-DTPA and Gd-EOB-DTPA. Conclusion:Gd-EOB-DTPA dynamic contrast enhancement in combination with hepatobiliary phase can provide more infor-mation in the diagnosis of SHCC which showed iso/hyper-intensity in delayed phase of Gd-DTPA,and thus may improve the diagnostic accuracy of atypical SHCC.