CAJ | 학술논문

目的：探讨在不同b值条件下，腮腺肿瘤中囊变区和实质区对表观扩散系数（ADC ）均值的影响。方法：回顾性分析经手术病理证实并于术前行DWI检查的32例腮腺囊实性肿瘤（良性肿瘤22例，恶性肿瘤10例）的影像资料。分别在b值为500和1000 s／mm2时，对肿瘤整体、肿瘤实质区和肿瘤囊变区的ADC均值进行测量，并进行统计学分析。结果：b＝500 s／mm2时，肿瘤整体部分的ADC均值为（1．73±0．35）×10-3mm2／s，实质部分为（1．35±0．23）×10-3mm2／s，囊变部分为（2．44±0．31）×10-3mm2／s。b＝1000 s／mm2时，肿瘤整体部分ADC 均值为（1．35±0．28）×10-3mm2／s，实质部分为（1．12±0．22）×10-3mm2／s，囊变部分为（1．94±0．30）×10-3mm2／s。上述不同取样方法所测肿瘤ADC均值差异有统计学意义（P＜0．01）。实质部分的ADC均值在腮腺多形性腺瘤、腺淋巴瘤、其他良性肿瘤和恶性肿瘤之间差异亦有统计学意义（P＜0．01）。结论：腮腺肿瘤中囊变区和实质区ADC均值不同，从腮腺肿瘤实质区取样的ADC均值能为其鉴别诊断提供更多有益信息。
목적：탐토재불동b치조건하，시선종류중낭변구화실질구대표관확산계수（ADC ）균치적영향。방법：회고성분석경수술병리증실병우술전행DWI검사적32례시선낭실성종류（량성종류22례，악성종류10례）적영상자료。분별재b치위500화1000 s／mm2시，대종류정체、종류실질구화종류낭변구적ADC균치진행측량，병진행통계학분석。결과：b＝500 s／mm2시，종류정체부분적ADC균치위（1．73±0．35）×10-3mm2／s，실질부분위（1．35±0．23）×10-3mm2／s，낭변부분위（2．44±0．31）×10-3mm2／s。b＝1000 s／mm2시，종류정체부분ADC 균치위（1．35±0．28）×10-3mm2／s，실질부분위（1．12±0．22）×10-3mm2／s，낭변부분위（1．94±0．30）×10-3mm2／s。상술불동취양방법소측종류ADC균치차이유통계학의의（P＜0．01）。실질부분적ADC균치재시선다형성선류、선림파류、기타량성종류화악성종류지간차이역유통계학의의（P＜0．01）。결론：시선종류중낭변구화실질구ADC균치불동，종시선종류실질구취양적ADC균치능위기감별진단제공경다유익신식。
Objective:The purpose of this study was to determine if there were different influences of solid and cystic constituents within parotid gland tumors on mean apparent diffusion coefficient (ADC)values.Methods:32 subjects who suffered from the solid-cystic parotid gland tumors (22 benign tumors and 10 malignant tumors)underwent conventional MR imaging and diffusion-weighted echo-planar MR imaging prior to surgery and pathologic verification.The mean ADC value of tumor emtirety,solid portion and cystic portion was measured with b-value at 500 and 1000s/mm2 respectively,and statistical analysis was performed.Results:The mean ADC values were significantly different (P<0.01)among the entirety (1.73 [b= 0,500s/mm2]and 1.35 [b= 0,1000s/mm2]×10-3mm2/s),solid portion (1.35[b= 0,500s/mm2]and 1.12 [b= 0,1000s/mm2]×10-3mm2/s),cystic region (2.44 [b= 0,500s/mm2]and 1.94 [b= 0,1000s/mm2]×10-3mm2/s) of these 32 parotid tumors.In addition,there were statistical differences (P<0.01)in the mean ADC values of solid por-tions among pleomorphic adenoma (10 cases),Warthin tumor (6 cases),other benign tumor (6 cases),and malignant tumor (10 cases).Conclusion:The different ROI samples (entirety,solid,and cystic portions)in the parotid tumors can result in different mean ADC values.It is believed that the mean ADC values obtained from the solid portions of parotid gland tumors may provide more valuable information for diagnosis.