CAJ | 학술논문

酵母β-葡聚糖是一类水不溶性免疫多糖，经硫酸酯化修饰后，所带有的亲水硫酸基团，不仅提高多糖水溶性，而且引起了生物活性的改变，表现出较强的抗病毒活性，其生物活性显著增强，属一类新型高效生物应答剂。论文综述了酵母β-葡聚糖经硫酸酯化修饰后生物学活性及其可能抗猪流感病毒机理，为进一步研究开发此类新型药物奠定基础。
효모β-포취당시일류수불용성면역다당，경류산지화수식후，소대유적친수류산기단，불부제고다당수용성，이차인기료생물활성적개변，표현출교강적항병독활성，기생물활성현저증강，속일류신형고효생물응답제。논문종술료효모β-포취당경류산지화수식후생물학활성급기가능항저류감병독궤리，위진일보연구개발차류신형약물전정기출。
Yeast beta glucan is a kind of water insoluble immune polysaccharide.After sulfated modifica-tion,it has hydrophilic sulfate groups,not only improves the water solubility,but also causes changes of bioactivity.Its biological activity was significantly enhanced,showing strong antiviral activity.It become a new efficient biological response agent.This paper reviewed the sulfated glucan activity and anti-swine flu-enza virus mechanism,which provide the base for further research and development of new medicines.